CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016

Dowell, Deborah; Haegerich, Tamara M.; Chou, Roger

doi:10.15585/mmwr.rr6501e1

Cited by 3,114 publications

(3,398 citation statements)

References 179 publications

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“…Fewer than 6,500 women per year in this study population received prescriptions for opioids during pregnancy. However, further study is required to determine the reason for prescribing opioids rather than other pain medication, and whether, for women with chronic pain, the prescribed dose and duration are consistent with CDC's opioid prescribing guideline (8) or, for women with other pain presentations, whether other prescribing recommendations are being followed. Additional analyses of opioid prescriptions should also include comparisons of all Medicaid-eligible women with those with continuous enrollment.…”

Section: Discussionmentioning

confidence: 99%

Opioid Prescriptions Among Women of Reproductive Age Enrolled in Medicaid — New York, 2008–2013

Gallagher¹,

Shin²,

Roohan³

2016

MMWR Morb. Mortal. Wkly. Rep.

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Exposure to opioids during pregnancy can lead to adverse infant outcomes, including neonatal abstinence syndrome (1) and birth defects (2). Ascertaining opioid prescriptions for women who become pregnant or have no indication of contraceptive use is important to determine the number of women who are at potential risk for adverse fetal outcomes. The New York State (NYS) Department of Health (DOH) analyzed data for women aged 15-44 years (i.e., reproductive-aged women) enrolled in Medicaid to examine opioid drug prescriptions during [2008][2009][2010][2011][2012][2013]. On the basis of Medicaid drug claims for any drug with an opioid ingredient, prescriptions were identified for the enrolled population of reproductive-aged women and for three subgroups: women whose diagnosis, procedure, and drug codes indicated contraceptive use or infertility; women who were not using contraceptives and not infertile; and women who had had a live birth during the reporting year. During 2008-2013, among all women of reproductive age, 20.0% received a prescription for a drug with an opioid component; the proportion was highest (27.3%) among women with an indication of contraceptive use or infertility, intermediate (17.3%) among women who had no indication of contraceptive use, and lowest (9.5%) among women who had had a live birth. Although New York's proportion of opioid prescriptions among female Medicaid recipients who had a live birth is lower than a recent U.S. estimate (3), these results suggest nearly one in 10 women in this group may have been exposed to opioids in the prenatal period.To understand patterns of prescribing opioid medications for women of reproductive age, NYS DOH examined Medicaid fee-for-service and managed care data during 2008-2013 for females aged 15-44 years who were continuously enrolled in Medicaid during each reporting year. NYS DOH used a list of medications derived from the NYS Medicaid formulary with First Data Bank hierarchical ingredient codes indicating opioids, and defined opioid prescription as any outpatient claim for a drug that contained an opioid ingredient for any woman during each reporting year (4). Live births were identified based on an International Classification of Diseases, Ninth Revision (ICD-9) primary diagnosis code indicating live birth (641.01-676.64, V27) and a principal procedure code indicating live birth (vaginal and cesarean delivery Current Procedural Terminology codes 59400, 59409, 59410, 59510, 59514, 59515, 59610, 59612, 59614, 59620, and 59622; ICD-9 procedure codes 73.51, 73.59, 74.0, 74.1, and 72.0-72.7) within 2 days of the diagnosis code.To determine the prenatal period, Medicaid records for a 1-year cohort of women were matched with vital statistics birth records. Among enrolled women who had a live birth, the mean gestational age in days for each pregnancy-related ICD-9 primary diagnosis code was calculated and used to compute the average prenatal period. Using this approach, the prenatal period was defined as the 280 days preceding the date of a live birth ...

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Section: Discussionmentioning

confidence: 99%

Opioid Prescriptions Among Women of Reproductive Age Enrolled in Medicaid — New York, 2008–2013

Gallagher¹,

Shin²,

Roohan³

2016

MMWR Morb. Mortal. Wkly. Rep.

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“…The Centers for Medicare & Medicaid Services recently issued recommendations on best practices for addressing prescription opioid overdose, focusing on steps insurers can take to reduce harms associated with methadone use for pain (8). In addition, CDC recommends that methadone not be the first choice for a long-acting opioid and that only clinicians who are familiar with methadone's unique risk profile and are prepared to educate and closely monitor their patients consider prescribing methadone for pain (9). Finally, health systems should consider the use of coordinated care plans to optimize evidence-based care.…”

Section: What Are the Implications For Public Health Practice?mentioning

confidence: 99%

Trends in Methadone Distribution for Pain Treatment, Methadone Diversion, and Overdose Deaths — United States, 2002–2014

Jones¹,

Baldwin²,

Manocchio³

et al. 2016

MMWR Morb. Mortal. Wkly. Rep.

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“…2 Chronic pain is defined as pain lasting beyond the time of tissue healing or for over three months. 3 Almost half of GP consultations involve some discussion of pain, usually relegated behind comorbidities such as obesity and diabetes or psychiatric and substance-use disorders. 4,5 Chronic pain challenges classic models of diagnosis and treatment.…”

Section: Introductionmentioning

confidence: 99%