“…In fungi, the roles of MED13 and of the kinase module have been studied most extensively in the yeasts Saccharomyces cerevisiae (Chi et al, 2001;Gonzalez et al, 2014;Krasley et al, 2006;Nelson et al, 2003;Raithatha et al, 2012;Shahi et al, 2010;Singh et al, 2006;van de Peppel et al, 2005), Schizosaccharomyces pombe (Linder et al, 2008;Zhu et al, 2006), and in human and plant pathogens such as Candida albicans (Lindsay et al, 2014;Uwamahoro et al, 2012;Zhang et al, 2013) and Cryptococcus neoformans (Wang et al, 2011). These studies revealed that the kinase module regulates hundreds of genes associated with carbon source utilization, stress responses, morphogenesis, filamentation and adhesion (Blankenship et al, 2010;Bluhm and Woloshuk, 2006;Chang et al, 2004;Cooper et al, 1999;Holstege et al, 1998;Larschan and Winston, 2005;Linder et al, 2008;Samuelsen et al, 2003;Uwamahoro et al, 2012;Wang et al, 2011;Wheeler et al, 2008;Zhou et al, 2010).…”