Abstract:The ubiquitous up-regulation of CEACAM6 in colon, pancreatic, breast and lung cancer is well established. This protein is known for its invasive and metastatic properties in pancreatic adenocarcinoma as well as in breast cancer. We propose that the overexpression of CEACAM5 and CEACAM6 are a pre-requisite for invasive and metastatic behavior of breast cancer. We have conducted bioinformatics studies to compare the expression profiles of CEA gene family members in sets of RNA-seq data for MCF10A (non-tumorigeni… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.