Cecropia pachystachya extract attenuated the renal lesion in 5/6 nephrectomized rats by reducing inflammation and renal arginase activity

Maquiaveli, Claudia do Carmo; Silva, Edson Roberto da; Rosa, L. Costa; Francescato, Heloı́sa Della Coletta; Júnior, João Francisco Lucon; Silva, Cleonice G.A.; Casarini, Dulce Elena; Ronchi, Fernanda Aparecida; Coimbra, Terezila Machado

doi:10.1016/j.jep.2014.09.042

Cited by 16 publications

(12 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, pretreatment with both rhizomes prevented the increase of arginase activity in hypertensive rats. Previous studies have reported up-regulation of arginase activity and decreased NO in hypertension (Bagnost et al, 2008(Bagnost et al, , 2010Maquiaveli et al, 2014). This result is in agreement with recent studies that inhibition of arginase activity is crucial for the management of hypertension (Bagnost et al, 2008(Bagnost et al, , 2010Maquiaveli et al, 2014).…”

Section: Discussionsupporting

confidence: 92%

“…Previous studies have reported up-regulation of arginase activity and decreased NO in hypertension (Bagnost et al, 2008(Bagnost et al, , 2010Maquiaveli et al, 2014). This result is in agreement with recent studies that inhibition of arginase activity is crucial for the management of hypertension (Bagnost et al, 2008(Bagnost et al, , 2010Maquiaveli et al, 2014). However, several authors have reported dietary plant phenolics exhibited inhibitory effect on arginase activity (Kim et al, 2013;Manjolin, dos Reis, Maquiaveli, Santos-Filho, & Da Silva, 2013).…”

Section: Discussionsupporting

confidence: 89%

See 1 more Smart Citation

Effect of dietary supplementation of ginger and turmeric rhizomes on angiotensin-1 converting enzyme (ACE) and arginase activities in L-NAME induced hypertensive rats

Akinyemi

Thomé

Morsch

et al. 2015

Journal of Functional Foods

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 89%

Effect of dietary supplementation of ginger and turmeric rhizomes on angiotensin-1 converting enzyme (ACE) and arginase activities in L-NAME induced hypertensive rats

Akinyemi

Thomé

Morsch

et al. 2015

Journal of Functional Foods

View full text Add to dashboard Cite

“…It is also used as a diuretic (Rocha et al 2007). Pharmacological activities were reported in extant studies including the development of anxiolytic, antidepressant (Velá zquez et al, 2003;Consolini et al, 2006;Gazal et al, 2014;Ortmann et al, 2016), hypoglycemic (Aragã o et al, 2010), antioxidant (Consolini et al, 2006;Farias et al, 2013;Souza et al, 2014;, cardiotonic (Consolini & Migliori, 2005;Gazal et al, 2014), sedative (Hikawczuk et al, 1998), anti-inflammatory (Pacheco et al, 2014;Maquiaveli et al, 2014), antimicrobial (Souza et al, 2014), and leishmanicidal (Cruz et al, 2013) properties for aqueous and alcoholic extracts prepared by infusion or maceration of C. pachystachya leaves.…”

Section: Introductionmentioning

confidence: 99%

Extraction of Cecropia Pachystachya Leaves by Supercritical Carbon Dioxide: Kinetics, Phytochemical Characterization, Antibacterial and Antioxidant Activities

Hoscheid

Otênio

Lourenço

et al. 2020

JAS

View full text Add to dashboard Cite

Cecropia pachystachya Trécul is popularly known in Brazil as embaúva or embaúba. Pharmacological activities were reported in extant studies including the development of anxiolytic, antidepressant, hypoglycemic, antioxidant, cardiotonic, sedative, anti-inflammatory, antimicrobial and leishmanicidal properties for aqueous and alcoholic extracts prepared by infusion or maceration of C. pachystachya leaves. However, there is a paucity of studies examining extracts of leaves of C. pachystachya obtained by supercritical fluid technology. This study evaluated the extraction of Cecropia pachystachya oil using supercritical carbon dioxide (CO2). Extractions were performed at 35 °C, 45 °C, and 55 °C and 14 MPa, 17 MPa, and 20 MPa. The extraction yield, characteristics of the oil, antioxidant and antibacterial potentials were evaluated. The highest extraction yield obtained from C. pachystachya leaves was 1.48% using supercritical CO2 at 55 °C and 20 MPa. The main identified compounds include terpenoids (ursolic and pomolic acids, squalene and β-sitosterol). The most promising results for antibacterial activity relative to Staphylococcus aureus and antioxidant potentials were observed on the extract obtained at 55 °C and 14 MPa. The mathematical Sovová model satisfactorily represented the experimental data.

show abstract

“…Chlorogenic acid and orientin were the main compounds identified in AE and EtE of leaves, which have been previously shown to have an anti-inflammatory effect (Maquiaveli et al. 2014 ).…”

Section: Biological Activities and Chemical Compounds Reported In Thementioning

confidence: 94%

Selection of chemical markers for the quality control of medicinal plants of the genus Cecropia

Rivera-Mondragón

Ortíz

Bijttebier

et al. 2017

Pharmaceutical Biology

View full text Add to dashboard Cite

Context: Several Cecropia (Cecropiaceae) species are traditionally used in Latin America for the treatment of a variety of diseases including diabetes, arterial hypertension, asthma, bronchitis, anxiety, and inflammation. At present, a number of commercial products based on these plants have been introduced into the market with very little information on methods for guaranteeing their quality and safety.Objective: This work proposes potential chemical markers for the quality control of the raw materials of Cecropia obtusifolia Bertol., Cecropia peltata L., Cecropia glaziovii Snethl., Cecropia pachystachya Trécul, and Cecropia hololeuca Miq.Methods: The Herbal Chemical Marker Ranking System (Herb MaRS) developed by the National Institute of Complementary Medicine (NICM) at the University of Western Sydney was used for selecting chemical markers for the quality control of selected medicinal species of Cecropia. This review covers the period from 1982 to 2016.Results: Chlorogenic acid, flavonoidal glycosides (orientin, isoorientin, vitexin, isovitexin, and rutin), catechin, epicatechin, procyanidins (B2, B5, and C1), steroids (β-sitosterol), and triterpenoids (α-amyrin, pomolic, tormentic and ursolic acids) were selected as chemical markers for the quality control of the leaves.Conclusion: It is necessary to establish comprehensive standards for guaranteeing quality, safety and efficacy of herbal drugs. The selection of adequate chemical markers for quality control purposes requires a good knowledge about the chemical composition of medicinal plants and their associated biological properties. To the best of our knowledge this review article is the first to address the identification and quantitative determination of the chemical markers for the genus Cecropia.

show abstract

Cecropia pachystachya extract attenuated the renal lesion in 5/6 nephrectomized rats by reducing inflammation and renal arginase activity

Cited by 16 publications

References 25 publications

Effect of dietary supplementation of ginger and turmeric rhizomes on angiotensin-1 converting enzyme (ACE) and arginase activities in L-NAME induced hypertensive rats

Effect of dietary supplementation of ginger and turmeric rhizomes on angiotensin-1 converting enzyme (ACE) and arginase activities in L-NAME induced hypertensive rats

Extraction of Cecropia Pachystachya Leaves by Supercritical Carbon Dioxide: Kinetics, Phytochemical Characterization, Antibacterial and Antioxidant Activities

Selection of chemical markers for the quality control of medicinal plants of the genus Cecropia

Contact Info

Product

Resources

About