Cefadroxil

Tanrisever, B; Santella, P J

doi:10.2165/00003495-198600323-00003

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1989

2023

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Cited by 35 publications

(1 citation statement)

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“…Due to its bactericidal activity, cefadroxil monohydrate is used as an antibacterial agent to treat various infections, such as urinary tract infections. 38 In this study, only the aromatic protons H-10/H-14 of compound 5 showed interactions with the protein, and received 100% saturation. The GEM results revealed the close proximity of H-10/H-14 with the protein residues (Fig.…”

Section: Resultsmentioning

confidence: 67%

Identification of new inhibitors of NS5 from dengue virus using saturation transfer difference (STD-NMR) and molecular docking studies

et al. 2023

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Section: Resultsmentioning

confidence: 67%

Identification of new inhibitors of NS5 from dengue virus using saturation transfer difference (STD-NMR) and molecular docking studies

et al. 2023

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Effect of Timing of Food on Absorption of Cefpodoxime Proxetil

Borin

Driver

Forbes

1995

The Journal of Clinical Pharma

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The effect of a high-fat meal and the timing of this meal on the absorption of a 400-mg oral dose of cefpodoxime proxetil was evaluated in 20 healthy, adult, male volunteers in a four-way crossover study. The area under the plasma concentration-time curve, peak plasma concentration, and urinary recovery were significantly greater (P = .0001) after administration of cefpodoxime proxetil tablets with and 2 hours after a meal relative to dosing under fasted conditions or 1 hour before a meal. The time to peak concentration did not differ significantly among treatments, which suggests that food did not affect the rate of drug absorption. These results indicate that absorption of cefpodoxime proxetil is enhanced when tablets are taken with food or shortly after a meal.

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