Cefamandole versus cefonicid prophylaxis in cardiovascular surgery: A prospective study

Gelfand, Mikhail S.; Simmons, Bryan P.; Schoettle, Philip B.; Harrington, O. Brewster; MARTIN, FRANK; Owen, Edmond W.; Craft, Rebecca B.; Amarshi, Naseem

doi:10.1016/0003-4975(90)90250-a

Cited by 13 publications

(1 citation statement)

References 25 publications

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“…Moreover, cefonicid has been found inferior to other cephalosporins for prophylaxis of surgical and nonsurgical infection following cardiovascular surgery. 14 On the other hand, the fact that the prophylaxis regimen remained unchanged throughout the pre-intervention period suggests that the peaking of device-associated infections during 2001 involved additional factors and makes the contribution of prophylaxis optimization during intervention somewhat questionable.…”

Section: June 2004mentioning

confidence: 99%

Prevention of Infections Associated With Permanent Cardiac Antiarrhythmic Devices by Implementation of a Comprehensive Infection Control Program

Borer¹,

Gilad²,

Hyam

et al. 2004

Infect. Control Hosp. Epidemiol.

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Section: June 2004mentioning

confidence: 99%

Prevention of Infections Associated With Permanent Cardiac Antiarrhythmic Devices by Implementation of a Comprehensive Infection Control Program

Borer¹,

Gilad²,

Hyam

et al. 2004

Infect. Control Hosp. Epidemiol.

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Antimicrobial Prophylaxis for Surgical Wounds

Page

Bohnen²,

Fletcher³

et al. 1993

Arch Surg

466

261

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Prophylactic administration of antibiotics can decrease postoperative morbidity, shorten hospitalization, and reduce the overall costs attributable to infections. Principles of prophylaxis include providing effective levels of antibiotics in the decisive interval, and, in most instances, limiting the course to intraoperative coverage only. Use in The National Research Council clean contaminated operations is appropriate and, in many instances, has been proven beneficial. Antibiotic prophylaxis is also indicated for clean operations, such as those involved with insertion of prosthetic devices, that are associated with low infection risk and high morbidity. Extension of antibiotic prophylaxis to other categories of clean wounds should be limited to patients with two or more risk factors established by criteria in the study of the efficacy of nosocomial infection control (SENIC) because the baseline infection rate in these patients is high enough to justify their use. Cefazolin (or cefoxitin when anaerobic coverage is necessary) remains the mainstay of prophylactic therapy. Selection of an alternate agent should be based on specific contraindications, local infection control surveillance data, and the results of clinical trials. Newer criteria for determining the risk of "site infection" (wound and intracavitary) are in evolution and may lead to modification of these recommendations over the next several years.

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Interventions to prevent surgical site infection in adults undergoing cardiac surgery

Rogers,

Vaja,

Bleetman

et al. 2024

Cochrane Database of Systematic Reviews

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Cefamandole versus cefonicid prophylaxis in cardiovascular surgery: A prospective study

Cited by 13 publications

References 25 publications

Prevention of Infections Associated With Permanent Cardiac Antiarrhythmic Devices by Implementation of a Comprehensive Infection Control Program

Prevention of Infections Associated With Permanent Cardiac Antiarrhythmic Devices by Implementation of a Comprehensive Infection Control Program

Antimicrobial Prophylaxis for Surgical Wounds

Interventions to prevent surgical site infection in adults undergoing cardiac surgery

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