2022
DOI: 10.34172/apb.2023.032
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Cefazolin-Loaded Double-Shelled Hollow Mesoporous Silica Nanoparticles/Polycaprolactone Nanofiber Composites: A Delivery Vehicle for Regenerative Purposes

Abstract: As important challenges in burn injuries, infections often lead to delayed and incomplete healing. Wound infections with antimicrobial-resistant bacteria are other challenges in the management of wounds. Hence, it can be critical to synthesize scaffolds that are highly potential for loading and delivering antibiotics over long periods. Methods: Double-shelled hollow mesoporous silica nanoparticles (DSH-MSNs) were synthesized and loaded with cefazolin. Cefazolin-loaded DSH-MSNs (Cef*DSH-MSNs) were incorporated … Show more

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Cited by 3 publications
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“…Hollow mesoporous silica nanoparticles (HMSNs) are also outstanding gene and drug delivery system because of the unique hollow mesoporous structure. [167][168][169][170][171][172] A polyamidoamine-aptamer-coated HMSNs was reported to co-deliver sorafenib and pCas9. 173 In HepG2 cells, the SEHPA NPs demonstrated a nearly 66.3% gene knockout efficacy.…”
Section: Inorganic Materials-based Nanotechnologymentioning
confidence: 99%
“…Hollow mesoporous silica nanoparticles (HMSNs) are also outstanding gene and drug delivery system because of the unique hollow mesoporous structure. [167][168][169][170][171][172] A polyamidoamine-aptamer-coated HMSNs was reported to co-deliver sorafenib and pCas9. 173 In HepG2 cells, the SEHPA NPs demonstrated a nearly 66.3% gene knockout efficacy.…”
Section: Inorganic Materials-based Nanotechnologymentioning
confidence: 99%