RSC Adv.
 2024
DOI: 10.1039/d4ra04302b
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Cefiderocol susceptibility endows hope in treating carbapenem-resistant Pseudomonas aeruginosa: insights from in vitro and in silico evidence

Soumya Basu,
Gayathri Ashok,
Soumyadip Ghosh
et al.

Abstract: Clinical carbapenemase-positive Pseudomonas aeruginosa strains showing pan-β-lactam resistance had stabilizing mutations in penicillin-binding protein-3. Cefiderocol however showed efficacy with low MIC-values due to multi-target specificity.

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