“…The synergistic activity of vancomycin and cefpirome has been thoroughly investigated using in vitro tests: the chequerboard procedure and the time kill method [3,6,7]. Furthermore, Raymond et al reported bacteriologic eradication of a mixed infection including MRSA and Enterobacter cloacae with this combination [8]. Our results confirm, using the time kill test, the synergistic activity of both drugs against GR-MRSA and GS-MRSA with cefpirome concentrations which can be achieved in serum [8].…”