Ceftriaxone treatment of complicated urinary tract infections as a risk factor for enterococcal re-infection and prolonged hospitalization: A 6-year retrospective study

Karlović, Kristian; Nikolić, Jadranka; Arapović, Jurica

doi:10.17305/bjbms.2018.3544

Cited by 5 publications

(4 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This medication is often administered to patients with CAUTI caused by Enterococcus spp., elderly patients, and those who experience urinary tract infections due to catheterization. These results are supported by previous study by Karlović et al (2018).…”

Section: Patterns Of Antibiotic Usesupporting

confidence: 93%

Bacterial Profile and Antibiotic Use in Catheter-Associated Urinary Tract Infection Patients at a Tertiary Referral Hospital in Surabaya, Indonesia

Ahmad Veri Erianto,

Tri Pudy Asmarawati,

Agung Dwi Wahyu Widodo

et al. 2023

FMI

View full text Add to dashboard Cite

Highlights: This study examined patients with catheter-associated urinary tract infections (CAUTI) to find the prevalent bacteria and the frequency of antibiotic use. Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli sensitive to amikacin was found to be the most common pathogen in CAUTI, while ceftriaxone was the most commonly used antibiotic. Abstract Catheter-associated urinary tract infection (CAUTI) is the most typical type of infection associated with healthcare. This infection constitutes a significant health problem due to its complications and frequent recurrence. The high annual incidence of CAUTI leads to infectious complications and a high cost of treatment. Antibiotic-resistant bacteria further complicate the problem because multiresistant pathogenic bacteria are often responsible for these infections. Moreover, the lack of a comprehensive case reporting system in Indonesia hinders the determination of CAUTI incidence. This study aimed to determine the bacterial profile and antibiotic use in CAUTI patients (n=22) at the Internal Medicine Inpatient Unit of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. This retrospective descriptive study collected data from patient medical records to describe the incidence, type of bacteria, sensitivity patterns, and antibiotic use in CAUTI patients. The data collection process included collecting medical records, recording information on data collection sheets, and recapitulating and analyzing the data. The criteria for CAUTI diagnosis were a bacterial count of ≥105 CFU/mL and a catheterization that lasted more than 48 hours. Samples were selected using non-probability sampling, also known as saturation sampling. Meanwhile, variables analyzed in this study were the type of pathogenic bacteria, antibiotics used, age, and sex. Descriptive analysis was employed to analyze the data. The findings suggested that the most common bacteria were Escherichia coli, with eight of nine bacteria showing extended-spectrum beta-lactamase (ESBL) production. Female patients aged 35–65 years were the majority of the CAUTI patients. Amikacin was the antibiotic with the highest sensitivity (90.9%), while ceftriaxone was the most common type of antibiotic administered to the patients. In addition, intravenous (IV) administration was the most common route of antibiotic administration, with an average therapy duration of seven days. In conclusion, identifying the type of pathogenic bacteria and performing antibiotic susceptibility testing can help minimize antibiotic resistance and prevent more severe complications in CAUTI patients.

show abstract

Section: Patterns Of Antibiotic Usesupporting

confidence: 93%

Bacterial Profile and Antibiotic Use in Catheter-Associated Urinary Tract Infection Patients at a Tertiary Referral Hospital in Surabaya, Indonesia

Ahmad Veri Erianto,

Tri Pudy Asmarawati,

Agung Dwi Wahyu Widodo

et al. 2023

FMI

View full text Add to dashboard Cite

show abstract

“…UTI najčešće počinje kao infekcija bešike, ali se vrlo brzo razvija i obuhvata bubrege što na kraju može dovesti do zatajenja bubrega. 2 Na osnovu mesta infekcije UTI se najčešće klasifikuju u kategorije bolesti: cistitis (mokraćna bešika), pijelonefritis (bubreg) i bakteriurija (urin). 1 Seksualno aktivne žene koje imaju normalan anatomskofiziološki urinarni trakt, češće oboljevaju od nekomplikovanih urinarnih infekcija, dok se kod pacijenata sa drugim osnovnim bolestima poput dijabetesa, pacijenata gde je bila potrebna prolongirana upotreba antibiotika, češće javljaju komplikovane infekcije.…”

Section: Uvodunclassified

Frequency of causative agents of urinary tract infections

Bogdanović¹,

Zlatković²,

Zlatanović³

et al. 2022

PONS

View full text Add to dashboard Cite

Objective. Every year, around 150 million people worldwide are diagnosed with some type of urinary tract infection. Urinary tract infections are the second most common, after respiratory infections. The aim of this paper is the microbiological analysis of the urine of primary health care patients on the territory of the municipality of Prokuplje. Methods. A six-month analysis was conducted retrospectively and included the isolation and identification of bacterial and fungal pathogens of urinary infections. Results. A total of 706 samples were collected. Of the tested samples, 388 (54.96%) were positive for pathogenic microorganisms. The most common pathogen is E. coli with a share of 67.52% in relation to the number of positively tested samples. Then follow Proteus spp. with 10.57%, Enterococcus spp. with 9.54%, Enterobacter spp. with 5.67%, Klebsiella spp. with 2.58%, Pseudomonas aeruginosa with 1.55%, S. aureus with 1.03% and C. albicans and Gardnerella vaginalis with 0.77% each in relation to the number of positively tested samples. According to the gender distribution of Gram-negative bacteria, the most common among women is Proteus spp. (82.93%), while in men the most common Klebsiella spp. (80%). Of the Gram-positive bacteria, S. aureus and Gardnerella vaginalis are 100% present only in the female population, as is C. albicans. Conclusion. When choosing antibiotic therapy for patients with urinary infections, it is very important to harmonize the therapy with the age and gender of the patient.

show abstract

“…Any leftover drug after therapy should be thrown away [1]. Dry medicinal syrup is 0.5-5 insoluble particles in a suitable Antibiotics, moisture-sensitive drugs, and paediatric pharmaceuticals are in dry syrup [2] . Oral dry powder combinations or granules are available for Amoxicillin trihydrate, Erythromycin ethylsuccinate, Dicloxacillin sodium, etc.…”

Section: Introductionmentioning

confidence: 99%

A Comprehensive Review on Amoxicilin and Clavulanic Acid as Potential Antibacterial Agent

Jeet

Kumar²,

Singh³

et al. 2022

Asian J Pharm Res Dev

View full text Add to dashboard Cite

Suspensions comprise finely divided medication particles (the suspensoid) spread uniformly in a vehicle with or without stabilisers and other ingredients. Conventional oral suspension is ready-to-use and does not require reconstitution. Dry syrup is more bioavailable than tablets and capsules because it dissolves in water outside the mouth and enters the GI tract. GIT absorbs suspension quickly: Amoxicillin and clavulanic acid have been used since the 1970s. Despite having the same half-life as amoxicillin, clavulanic acid is protein-bound and heat unstable. It causes gastrointestinal side effects, including Clostridium difficile infection, and restricts amoxicillin oral combination doses. Due to clavulanic acid's b-lactamase tendency, the first amoxicillineclavulanic acid ratio was 4:1; currently it's 2:1, 7:1, 14:1, and 16:1. Few ratio comparisons exist. Amoxicillineclavulanic acid is often used as empiric therapy for WHO's Priority Infectious Syndromes in adults and children, resulting in large consumption. Some of these syndromes may be handled with a delayed antibiotic prescription approach or amoxicillin alone.

show abstract

Ceftriaxone treatment of complicated urinary tract infections as a risk factor for enterococcal re-infection and prolonged hospitalization: A 6-year retrospective study

Cited by 5 publications

References 47 publications

Bacterial Profile and Antibiotic Use in Catheter-Associated Urinary Tract Infection Patients at a Tertiary Referral Hospital in Surabaya, Indonesia

Bacterial Profile and Antibiotic Use in Catheter-Associated Urinary Tract Infection Patients at a Tertiary Referral Hospital in Surabaya, Indonesia

Frequency of causative agents of urinary tract infections

A Comprehensive Review on Amoxicilin and Clavulanic Acid as Potential Antibacterial Agent

Contact Info

Product

Resources

About