Celiac Disease in India: Are They True Cases of Celiac Disease?

Abstract

Indian children with CD are true cases of CD. They present late, diarrhea is absent in 20% of cases, and AGA test results show 88% of children without false-positive results at a cutoff value of 10 U/mL. However, AGA test with 94% sensitivity at a cutoff value of 5 U/mL can be used as screening test to select suspected cases for further workup.

Celiac Disease Screening in Southern and East Asia

“…Most of the subsequent reports on CD came from the northern part of India (States of Punjab, Haryana, Delhi, Rajasthan, Uttar Pradesh), where wheat is the staple dietary cereal [6,7,8,9,10,11,12,13,14,25,26,27,28]. …”

“…Although there has been an increase in the number of publications on CD from the Asian region, there is a paucity of literature on its prevalence in most Asian nations, with the exception of India [6,7,8,9,10,11,12,13,14]. Additionally, few case reports and short reports are available from China, Pakistan and Japan [15,16,17,18,19,20].…”

Celiac Disease – A Case Series from North India

“…Anemia and short stature were more in comparison to Western studies, thereby reflecting delayed diagnosis [4]. However, short stature is less as compared to previous Indian study published a decade ago [5]. There is ongoing need to increase the awareness about the different presentations of the disease so as to enable early diagnosis.…”

The Prevalence and Clinico-Epidemiological Profile of Celiac Disease in Anaemic Children Admitted At a Tertiary Care Hospital of North West Rajasthan (India)

“…A study done by Patwari A. K. et al had shown that the mean age at the time of presentation was 6.67+ 2.37 years [23] . In a study by Poddar U et al mean age of 50 children with celiac disease was 6.3 + 2.6 years [24] . Result of our study in term of mean age of presentation are comparable with above mentioned studies.…”