Challenges in Parkinson's Disease 2016
DOI: 10.5772/63747
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Cell-Based Therapies for Parkinson’s Disease: Preclinical and Clinical Perspectives

Abstract: Parkinson's Disease (PD) is a highly prevalent neurodegenerative disease that affects millions of people globally and remains without definitive treatment. There have been many recent advances in cell-based therapy to replace lost neural circuitry and provide chronic biological sources of therapeutic agents to disease-affected brain regions. Early neural transplantation studies highlighted the challenges of immune rejection, graft integration, and the need for renewable, autologous graft sources. Neurotrophic … Show more

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