2011
DOI: 10.1002/dvdy.22684
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Cell biological regulation of division fate in vertebrate neuroepithelial cells

Abstract: Summary The developing nervous system derives from neuroepithelial progenitor cells that divide to generate all of the mature neuronal types. For the proper complement of cell types to form, the progenitors must produce postmitotic cells, yet also replenish the progenitor pool. Progenitor divisions can be classified into three general types: symmetric proliferative (producing two progenitors), asymmetric neurogenic (producing one progenitor and one postmitotic cell) and symmetric neurogenic (producing two post… Show more

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Cited by 33 publications
(31 citation statements)
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“…During vertebrate retinal patterning, apical-basal gradients of various signaling environments can control cell-type specification (Del Bene et al, 2008; reviewed by Willardsen and Link, 2011). Similar mechanisms may play a role in zebrafish retinal regeneration.…”
Section: Differentiation Of New Neurons and Gliamentioning
confidence: 99%
“…During vertebrate retinal patterning, apical-basal gradients of various signaling environments can control cell-type specification (Del Bene et al, 2008; reviewed by Willardsen and Link, 2011). Similar mechanisms may play a role in zebrafish retinal regeneration.…”
Section: Differentiation Of New Neurons and Gliamentioning
confidence: 99%
“…The centrosome in G1 cells is comprised of two centrioles, termed the mother and daughter centriole. Each of the two centrioles in the centrosome self-duplicates once during the cell cycle, but their rate of maturation is asymmetric [37]. Upon self-duplication, both centrioles become mother centrioles with newly associated daughter centrioles.…”
Section: Ciliary Proteins - Beyond the Ciliummentioning
confidence: 99%
“…During the development of the mammalian central nervous system, neural stem/progenitor cells generate neurons through a combination of asymmetric and symmetric divisions (Farkas and Huttner, 2008; Gotz and Huttner, 2005; Huttner and Kosodo, 2005; Willardsen and Link, 2011). All neurons of the mammalian central nervous system derive from a neuroepithelium.…”
Section: Characteristics Of Mammalian Stem Cellsmentioning
confidence: 99%