Cell-cycle and Age-Related Modulations of Mouse Chromosome Stiffness
Ning Liu,
Wenan Qiang,
Philip Jordan
et al.
Abstract:The intricate structure of chromosomes is complex, and many aspects of chromosome configuration/organization remain to be fully understood. Measuring chromosome stiffness can provide valuable insights into their structure. However, the nature of chromosome stiffness, whether static or dynamic, remains elusive. In this study, we analyzed chromosome stiffness in MI and MII oocytes. We revealed that MI oocytes had a ten-fold increase in stiffness compared to mitotic chromosomes, whereas chromosome stiffness in MI… Show more
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