Cell manipulation systems using dielectrophoretic process for diagnostic sensors

Abstract

This paper demonstrated the effectiveness of Dielectrophoresis (DEP) on microfluidic devices as part of diagnostic sensors. It was possible to focus bacterial cells into the intended area based on droplet evaporation on hydrophobic guide structure and DEP force with micro-patterned electrodes. Similarly, we dealt with separation of blood cells from whole blood so that plasma can be applied in many biomedical fields. The micro fluidic channels were attached on both sides of the device which includes electrodes for DEP and pore-array membrane. Micro-sized beads were experimented prior to realizing those two functions of DEP on biological cells.