2023
DOI: 10.3390/pharmaceutics15020661
|View full text |Cite
|
Sign up to set email alerts
|

Cell Proteomic Footprinting: Advances in the Quality of Cellular and Cell-Derived Cancer Vaccines

Abstract: In omics sciences, many compounds are measured simultaneously in a sample in a single run. Such analytical performance opens up prospects for improving cellular cancer vaccines and other cell-based immunotherapeutics. This article provides an overview of proteomics technology, known as cell proteomic footprinting. The molecular phenotype of cells is highly variable, and their antigenic profile is affected by many factors, including cell isolation from the tissue, cell cultivation conditions, and storage proced… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2

Citation Types

0
2
0

Year Published

2023
2023
2023
2023

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(2 citation statements)
references
References 100 publications
0
2
0
Order By: Relevance
“…9 These studies have significant implications for targeted therapy, immunotherapy, and vaccine development. 10 Therefore, activity-based protein profiling (ABPP) is emerging as a reliable chemoproteomic technology associated with an analytical and synthetic toolbox for chemically profiling the proteome. Unfortunately, selectively enriching the CSPs remains technically challenging because of their low abundance and the absence of specific capture motifs.…”
Section: ■ Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“…9 These studies have significant implications for targeted therapy, immunotherapy, and vaccine development. 10 Therefore, activity-based protein profiling (ABPP) is emerging as a reliable chemoproteomic technology associated with an analytical and synthetic toolbox for chemically profiling the proteome. Unfortunately, selectively enriching the CSPs remains technically challenging because of their low abundance and the absence of specific capture motifs.…”
Section: ■ Introductionmentioning
confidence: 99%
“…Surface proteome studies are crucial for understanding the diversity and function of cell surface proteins. Recent studies have utilized advanced techniques to identify and quantify cell surface proteins in different cell types, including immune and cancer cells . These studies have significant implications for targeted therapy, immunotherapy, and vaccine development . Therefore, activity-based protein profiling (ABPP) is emerging as a reliable chemoproteomic technology associated with an analytical and synthetic toolbox for chemically profiling the proteome.…”
Section: Introductionmentioning
confidence: 99%