Cell Temperature Measurement for Biometabolism Monitoring

Abstract

Temperature is an important factor in the process of life, as thermal energy transfer participates in all biological events in organisms. Due to technical limitations, there is still a lot more information to be explored regarding the correlation between life activities and temperature changes. In recent years, the emergence of a variety of new temperature measurement methods has facilitated further research in this field. Here, we introduce the latest advances in temperature sensors for biological detection and their related applications in metabolic research. Various technologies are discussed in terms of their advantages and shortcomings, and future prospects are presented.

Living Sample Viability Measurement Methods from Traditional Assays to Nanomotion

“…The calorimeter principle makes it impossible to set up a sample development environment for an extended time. As a result, calorimeters are unsuitable for research in which living sample viability must be maintained for an extended period of time [ 113 ]. The most severe limitations of power resolution are thermal noise and noise created by microcalorimeter sensors.…”

Multiple ratiometric nanothermometry using semiconductor BiFeO3 nanowires and quantitative validation of thermal sensitivity

“…Let us denote A (1) = a 1 , A (2) = a 2 , A (3) = a 3 Overall thermal sensitivity of LIR ratio (E2/E1, E2/E3, and E2/E4) over the temperature range of 300-440 K = 3 k=1 i k i=1 A (k) i A (k) ij ; for j = 1, 2, 3;…”

“…of measuring temperature and developing temperature probes is important for applications in emerging environments including nanobiotechnology and integrated optics[1][2][3][4][5]. Currently Page 2 of 12 Prashanthi et al Micro and Nano Systems Letters (2022) 10:1…”

Luminescent upconversion nanoparticles evaluating temperature-induced stress experienced by aquatic organisms owing to environmental variations

“…Monitoring temperature changes can act as a proxy measurement for environmental stress factors affecting living organisms. Factors such as changing metabolic rates are reflected in temperature changes, as well as the direct influence of the environmental temperature ( Shadwick et al., 2013 ; Rajagopal et al., 2019 ; Wang et al., 2021 ). A precise and accurate in vivo temperature measurement technique can, therefore, play an important role in monitoring organisms’ health.…”