“…After the accumulation of blastemalike cells with activation of the prx1 limb-specific enhancer around the original wound, nearly normal dermal tissue with maturating (newly formed) secretion glands is formed in a Xenopus laevis froglet (Yokoyama et al, 2011). Finally, almost complete skin including secretion glands and dermis is regenerated and subcutaneous myofibrillar organization around the original wound is recovered in an anuran amphibian, a Xenopus laevis froglet (Otsuka-Yamaguchi et al, 2017;Suzuki et al, 2005;Yokoyama et al, 2011), as well as in a urodele amphibian, an axolotl (Levesque et al, 2010;Seifert, Monaghan, et al, 2012), without formation of an obvious scar. Finally, almost complete skin including secretion glands and dermis is regenerated and subcutaneous myofibrillar organization around the original wound is recovered in an anuran amphibian, a Xenopus laevis froglet (Otsuka-Yamaguchi et al, 2017;Suzuki et al, 2005;Yokoyama et al, 2011), as well as in a urodele amphibian, an axolotl (Levesque et al, 2010;Seifert, Monaghan, et al, 2012), without formation of an obvious scar.…”