2022
DOI: 10.1101/2022.12.14.520462
|View full text |Cite
Preprint
|
Sign up to set email alerts
|

Cellular and Fibrillar Collagen Analyses in an Animal Model of Retinal Detachment-Related Proliferative Vitreoretinopathy Reveals a Defined Transition to Chronic Fibrosis

Abstract: Purpose: Proliferative vitreoretinopathy (PVR) is the most common cause of failure of surgically repaired rhegmatogenous retinal detachment (RRD). Chemically-induced and cell-injection PVR models do not fully simulate the clinical characteristics of PVR in the post-RRD context. There is an unmet need for translational models in which to study mechanisms and treatments specific to RRD-PVR. Methods: RRD-PVR was induced in adult Dutch Belted rabbits. Posterior segments of enucleated globes were fixed or processed… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 53 publications
(86 reference statements)
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?