Cellular and Mediator Mechanisms of Allergic Inflammation

Prochnau, J.J.; Busse, William W.; Holgate, Stephen T.

doi:10.1016/b978-0-323-03227-8.50026-3

Allergy 2006

DOI: 10.1016/b978-0-323-03227-8.50026-3

|View full text |Cite

Cellular and Mediator Mechanisms of Allergic Inflammation

J.J. Prochnau¹,

William W. Busse²,

Stephen T. Holgate³

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2009

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

From pharmacokinetics to therapeutics

Church¹,

Gillard

Sargentini‐Maier

et al. 2009

Drug Metabolism Reviews

View full text Add to dashboard Cite

Whilst pharmacokinetics describe the relationship between dose levels and concentration-time profiles of a drug in the body and pharmacodynamics describe the concentration-response relationships, pharmacokinectics-pharmacodynamics(PK-PD) models link these two items providing a framework for modelling the time course of drug response. In this chapter, PK-PD models, describing the therapeutic effects of drugs used for the therapy of allergic diseases have been reviewed. Emphasis was given also to the description of the receptor occupancy, which is tightly related to the downstream clinical response. PK - PD models describing unwanted effects were also commented. An integrated use of these models allows choosing appropriate dosing regimens and providing an objective evaluation of the benefit/risk balance.

show abstract

From pharmacokinetics to therapeutics

Church¹,

Gillard

Sargentini‐Maier

et al. 2009

Drug Metabolism Reviews

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Cellular and Mediator Mechanisms of Allergic Inflammation

Cited by 1 publication

References 0 publications

From pharmacokinetics to therapeutics

From pharmacokinetics to therapeutics

Contact Info

Product

Resources

About