Cellular and Molecular Actions of Juvenile Hormone. II. Roles of Juvenile Hormone in Adult Insects

Wyatt, G.R.; Davey, K. G.

doi:10.1016/s0065-2806(08)60030-2

Cited by 458 publications

(395 citation statements)

References 599 publications

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“…In addition to the metamorphic action, JH has a wide variety of actions in reproduction, caste differentiation, migratory behavior, and diapause (Riddiford, 1994;Jones, 1995;Wyatt and Davey, 1996). The mode of JH action, however, is still not fully understood (Wheeler and Nijhout, 2003).…”

Section: Introductionmentioning

confidence: 99%

Interaction of proteins involved in ecdysone and juvenile hormone signal transduction

Bitra

Palli

2008

Arch Insect Biochem Physiol

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Ecdysteroids and juvenile hormones (JH) regulate a variety of developmental, physiological, behavioral, and metabolic processes. Ecdysteroids function through a heterodimeric complex of two nuclear receptors, ecdysone receptor (EcR) and ultraspiracle (USP). An 85 kDa protein identified in Drosophila melanogaster methoprene‐tolerant (Met) mutant binds to JH III with high affinity, and the mutant flies are resistant to juvenile hormone analog (JHA), methoprene. Reporter assays using the yeast two‐hybrid system were performed in order to study the molecular interactions between EcR, USP and Met. As expected, EcR fused to the B42 activation domain and USP fused to the LexA DNA binding domain interacted with each other and supported induction of the reporter gene in the presence of stable ecdysteroid analog, RG‐102240 or steroids, muristerone A and ponasterone A. The USP:USP homodimers supported expression of the reporter gene in the absence of ligand, and there was no significant increase in the reporter activity after addition of a JHA, methoprene. Similarly, Met:Met homodimers as well as Met:EcR and Met:USP heterodimers induced reporter activity in the absence of ligand and addition of ecdysteroid or JH analogs did not increase the reporter activity regulated by either homodimers or heterodimers of Met protein. Two‐hybrid assays in insect cells and in vitro pull‐down assays confirmed the interaction of Met with EcR and USP. These data suggest that the proteins that are involved in signal transduction of ecdysteroids (EcR and USP) and juvenile hormones (Met) interact to mediate cross‐talk between these two important hormones. Arch. Insect Biochem. Physiol. 2008. © 2008 Wiley‐Liss, Inc.

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Section: Introductionmentioning

confidence: 99%

Interaction of proteins involved in ecdysone and juvenile hormone signal transduction

Bitra

Palli

2008

Arch Insect Biochem Physiol

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“…Flight muscle histolysis is a crucial developmental event that affects reproductive capacity, dispersal potential, and individual survival characteristics of insects (Finlayson, 1975;Wyatt and Davey, 1996;Marden, 2000). Either direct or facultative relationships between histolysis and reproductive maturity are seen in many insects (Pener, 1985).…”

Section: Introductionmentioning

confidence: 99%

“…Early studies demonstrated that inhibition of de novo protein expression was able to block PCD (Lockshin, 1969;Tata, 1966). Although recognized as an example of PCD (Gutman et al, 1974,Lockshin, 1985Wyatt and Davey, 1996), little attention has been directed toward cell death pathways as mechanisms of flight muscle histolysis. Active requirements for protein synthesis and ubiquitin proteolysis during degeneration of aphid flight muscles were investigated in relationship to PCD (Kobayshi and Ishikawa, 1994).…”

Section: Introductionmentioning

confidence: 99%

Programmed cell death in flight muscle histolysis of the house cricket

Oliver

Albury

Mousseau

2007

Journal of Insect Physiology

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We have characterized the process of flight muscle histolysis in the female house cricket, Acheta domesticus, through analysis of alterations of tissue wet weight, total protein content, and percent shortening of the dorsal longitudinal flight muscles (DLMs). Our objectives were to (1) define the normal course of histolysis in the cricket, (2) analyze the effects of juvenile hormone (JH) removal and replacement, (3) determine the effects of cycloheximide treatment, and (4) examine patterns of protein expression during histolysis.Our results suggest that flight muscle histolysis in the house cricket is an example of an active, developmentally regulated cell death program induced by an endocrine signal. Initial declines of total protein in DLMs indicated the JH signal that induced histolysis occurred by Day 2 and that histolysis was essentially complete by Day 3. Significant reductions in tissue weight and percent muscle shortening were observed in DLMs from Day 3 crickets. Cervical ligation of Day 1 crickets prevented histolysis but this inhibition could be reversed by continual topical treatments with methoprene (an active JH analog) although ligation of Day 2 crickets did not prevent histolysis. A requirement for active protein expression was demonstrated by analysis of synthesis block by cycloheximide and short-term incorporation of 35 S-methionine. Treatment with cycloheximide prevented histolysis. Autofluorographic imaging of DLM proteins separated by electrophoresis revealed apparent coordinated regulation of protein expression.

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“…In contrast with the large knowledge on how JH participate in oogenesis in female insects, its role in the maturation of male reproductive organs has been investigated only partially so far. In many insects JH does not appear to regulate spermiogenesis in the testes (Wyatt and Davy, 1996); on the other hand, JH may promote the secretory activity of accessory glands (Harano, 2013). These observations indicate that neuroendocrine mechanisms differ between males and females, highlighting the need to extend the analysis of the effect of one or more parasites also to the neglected male social Hymenoptera .…”

Section: Discussionmentioning

confidence: 99%

Subtle effect of Xenos vesparum (Xenidae, Strepsiptera) on the reproductive apparatus of its male host: Parasite or parasitoid?

Beani

Marchini

Cappa

et al. 2017

Journal of Insect Physiology

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A B S T R A C TParasitic castration is an adaptive strategy where parasites usurp the hosts' reproductive physiology to complete their life cycle. The alterations in the host traits vary in their magnitude, from subtle changes in the host morphophysiology and behaviour to the production of complex aberrant phenotypes, which often depend on the host gender. The strepsipteran macroparasite Xenos vesparum induces dramatic behavioural and physiological changes in its female host, the paper wasp Polistes dominula, while its effect on the male phenotype is largely unknown.In this study we investigated how a single X. vesparum parasite influences the functional morphology of P. dominula male reproductive apparatus. We performed morphometry and ultrastructure characterization of corpora allata, testes, seminal vesicles and accessory glands in parasitized and unparasitized males, and also in young and old males to control for the effect of age on the natural deterioration of these organs. Our results show that age significantly affects the development of male reproductive apparatus. A low parasite load -one parasite per host is the common prevalence in the field -has only a marginal impact on the reproductive morphology of P. dominula males, affecting quantitatively but not qualitatively the protein content of male accessory glands. Thus, in male P. dominula wasps, X. vesparum appears to behave as a true "parasite", in clear opposition to the role of "parasitoid" that it takes in female hosts where castration causes the reproductive death.

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Cellular and Molecular Actions of Juvenile Hormone. II. Roles of Juvenile Hormone in Adult Insects

Cited by 458 publications

References 599 publications

Interaction of proteins involved in ecdysone and juvenile hormone signal transduction

Interaction of proteins involved in ecdysone and juvenile hormone signal transduction

Programmed cell death in flight muscle histolysis of the house cricket

Subtle effect of Xenos vesparum (Xenidae, Strepsiptera) on the reproductive apparatus of its male host: Parasite or parasitoid?

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