2012
DOI: 10.5897/jmpr11.122
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Cellular antioxidant and antiproliferative activity of ethanolic extract of Coleus tuberosus

Abstract: Ethanolic extract of both the flesh and peel of Coleus tuberosus (EEPC) were evaluated for cellular antioxidant activity based on 2,7,-diacetate dichlorofluorescein (DCFH) oxidation, and antiproliferative activity based on 3-(4,5-dimethylthiazol-2)-2,5-diphenyltetrazolium bromide (MTT) assay, using human breast cancer MCF-7 cells. The result showed that antioxidant and antiproliferative activity of EEPC was higher than EEFC. Its bioactive compounds ursolic acid was higher than oleanolic acid. The antioxidant a… Show more

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“…Hsum et al (2010) also reported it to contain maslinic acid possessing anti-cancer activity. In addition, the tuber has compounds that possess antioxidant and anti-cancer properties (Nugraheni et al, 2011). Its capability to decrease blood glucose and lipid levels is much better when boiled or made into flakes (Nugraheni et al, 2015).…”
Section: Introductionmentioning
confidence: 99%
“…Hsum et al (2010) also reported it to contain maslinic acid possessing anti-cancer activity. In addition, the tuber has compounds that possess antioxidant and anti-cancer properties (Nugraheni et al, 2011). Its capability to decrease blood glucose and lipid levels is much better when boiled or made into flakes (Nugraheni et al, 2015).…”
Section: Introductionmentioning
confidence: 99%