2003
DOI: 10.1021/bk-2003-0862.ch012
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Cellular Engineering of Escherichia coli for the Enhanced Protein Production by Fermentation

Abstract: In 1982, approval of FDA for Eli Lilly's recombinant human insulin was just the prelude to the use of Escherichia coli as a host strain for recombinant protein production. After two decades, although many alternative organisms such as mammalian and plant cells are now being used for recombinant protein production, E. coli still remains the most valuable host for the production of recombinant proteins because of the advantages such as fast growth, well--characterized genetics, availability of numerous vector sy… Show more

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