Cellulose‐Based Biomaterials: Chemistry and Biomedical Applications

Abstract

This review represents a fresh survey about cellulose‐based biomaterial for biomedical application, in which certain features that are essential to design potential biomedical materials. It illustrates their functionalizations, benefits, properties, and applications in the biomedical. Cellulose is produced from plants and alternative sources such as bacteria, algae, and fungi as well as animals where tunicate is the only animal source of cellulose. Biomedical materials based on cellulose attracts attention due to its unique physicochemical features and high biocompatibility. Thus, cellulose‐based biomaterials have wide potential to be used in large scale biomedical applications as a pioneering material that may be used alone or with other additives. Additionally, they are used in several biomedical applications such as drug delivery, wound dressing, and tissue engineering. However, cellulose is not extensively used in the biomedical industrial field, this may be due to the limitations of the full studies and the limitation of availability of clinical trials. Moreover, the biomaterials based on cellulose are a potential substrate for the 3D bioprinting field where the tissues and organs can be designed as prototype production. For all these reasons, this work will highlight the recent developments in the preparation methods of cellulose‐based biomaterials and their derivatives.

Advances in the Physico-Chemical, Antimicrobial and Angiogenic Properties of Graphene-Oxide/Cellulose Nanocomposites for Wound Healing

“…Among the biomaterials, cellulose is the most abundant, cheap, sustainable, chemical reactive and modifiable natural macromolecular compound on the Earth. It is a carbohydrate homopolymer, which is composed of repeating long linear chains of β -anhydro-D-glucopyranose units, linked together by an ether bond between -OH group of C4, and the C1 carbon atom, via a β -1,4-glycosidic bond, as represented in Figure 1 [ 17 ].…”

3D printing of polylactic acid: recent advances and opportunities

“…These polymers are a category from biomass sources rather than oleochemical sources [ 2 – 4 ]. Even though few such polymers were familiar for more than a century, they could not find broad applications because of production barriers, like cost and scale [ 5 ]. Synthetic biology advances have made such polymers more affordable to produce and hence more widespread [ 4 – 7 ].…”

Thermo- and pH-responsive cotton gauzes as drug delivery system obtained by gamma radiation and chemical initiator

“…Due to the high biocompatibility that this polymer exhibits, cellulose-based materials tend to be incorporated in biological systems and to be used in the evaluation, treatment, increase or replacement of any tissue, organ or body function (Vázquez et al 2021;Hasanin 2022). Among these materials of cellulosic origin, cotton gauze highlights because this material is primarily used in the biomedical eld especially as wound dressing derived from skin cuts, burns, ulcers or diabetes, amongst any others.…”