Cellulose degradation and carboxymethylcellulase production by Sporocytophaga myxococcoides grown in an air-lift fermenter

Vance, I.; Blayden, Sarah L.; Tampion, J.

doi:10.1007/bf00127259

Cited by 7 publications

(1 citation statement)

References 7 publications

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“…Vance et al 44 studied the growth of Sporocytophaga myxcoccoides using a medium containing 20 g/L insoluble cellulose powder (23-30 pm). They noted that the addition of the powder increased the oxygen mass transfer by affecting the gas hold-up and bubble size.…”

Section: Introductionmentioning

confidence: 99%

Two‐ and three‐phase mixing in a concentric draft tube gas‐lift fermentor

Kennard

Janekeh

1991

Biotech & Bioengineering

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Two- and three-phase mixing studies were carried out in a 44-L concentric draft tube gas-lift fermentor. It was proposed to use the fermentor for the production of solvents using immobilized bacteria. Bubble size, gas holdup, liquid velocities, circulation, and mixing times were determined for various superficial gas velocities in distilled water, starch, carboxymethyl cellulose, and ethanol solutions. The observed trends for two phase mixing were similar to other studies but the results were found to be more sensitive to liquid properties. This was possibly due to the large value of downcomer to riser area used in this study. Mixing in three phases highlighted the difficulty in predicting the effect of adding solids to the gas-liquid system. Results showed that the gas-lift fermentor was ideally suited to dealing with three phases but more work is necessary before accurate models can be developed to account for the effect of solids.

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Section: Introductionmentioning

confidence: 99%

Two‐ and three‐phase mixing in a concentric draft tube gas‐lift fermentor

Kennard

Janekeh

1991

Biotech & Bioengineering

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Investigation of the bacitracin biosynthesis in an airlift bioreactor

Roman

1993

Acta Biotechnologica

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Results of pilot plant studies using an external-loop airlift bioreactor (170 1 fermentation volume, liquid height-to-riser diameter: 27, loop-to-tower cross-section-area: 0.1225) have proven the relative merits of such a system in the bacitracin biosynthesis produced by the Bacillus licheniformis submerged aerobic cultivation. The results were compared to those obtained in a pilot-scale stirred-tank bioreactor with the same values of kLa. Excepting the aeration rate of 0.2vvm, the fermentation process performed at 0.5 w m and 1/0 wm, respectively, unfolded similarly in the two fermentation devices with respect to the cell mass production, substrate utilization and bacitracin production during the fermentation process. In the riser section of the airlift bioreactor, the dissolved oxygen levels were higher, while in the downcomer section they were lower than those realized in the stirred tank bioreactor. Power requirements of the airlift fermenter were by 17-64% lower than those for a mechanically agitated system, depending on the aeration rates, which led to an important energy saving. Moreover, the lack of mechanical devices in the airlift system provides safety and a more gentle environment for the cultivation of microorganisms.

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Cultivation of a filamentous mould in an airlift bioreactor

Roman

1995

Acta Biotechnologica

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Cephalosporin C biosynthesis was investigated in a pilot-plant external-loop airlift bioreactor for evaluating the capacity of this bioreactor to surpass the problems which arise from the morphology of the mould and the rheology of the broth.Some of the results were compared with those obtained in a stirred tank bioreactor.The dilution and the use of static mixers was necessary to overcome the effects of the high viscosities. The oxygen transfer rate represented 84% of that in the stirred bioreactor, but the efficiency of the power utilization was higher. The specific productivity of Cephalosporin C is comparable to that obtained in the stirred tank bioreactor, but the average specitic power consumption was found to be */3 of that in the stirred vessel.

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Cellulose degradation and carboxymethylcellulase production by Sporocytophaga myxococcoides grown in an air-lift fermenter

Cited by 7 publications

References 7 publications

Two‐ and three‐phase mixing in a concentric draft tube gas‐lift fermentor

Two‐ and three‐phase mixing in a concentric draft tube gas‐lift fermentor

Investigation of the bacitracin biosynthesis in an airlift bioreactor

Cultivation of a filamentous mould in an airlift bioreactor

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