Cellulose-Derived Oligomers Act as Damage-Associated Molecular Patterns and Trigger Defense-Like Responses

Souza, Clarice de Azevedo; Li, Shundai; Lin, Andrew Z.; Boutrot, Freddy; Großmann, Guido; Zipfel, Cyril; Somerville, Shauna

doi:10.1104/pp.16.01680

Cited by 215 publications

(206 citation statements)

References 112 publications

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“…OG recognition, likely through the EGF-like RLK WAK1, induces PTI-like defenses (Denoux et al, 2008;Brutus et al, 2010). Cutin monomers and cellulose-derived oligomers are also immunogenic (Fauth et al, 1998;Souza et al, 2017). Recognition of these cell-wall-derived DAMPs resembles TLR2/ TLR4/TLR6-mediated recognition of degradation products from extracellular matrix in mammals .…”

Section: Recognition Of Host Cell Alterations (Damps)mentioning

confidence: 99%

Pattern recognition receptors and signaling in plant–microbe interactions

2018

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SUMMARYPlants solely rely on innate immunity of each individual cell to deal with a diversity of microbes in the environment. Extracellular recognition of microbe-and host damage-associated molecular patterns leads to the first layer of inducible defenses, termed pattern-triggered immunity (PTI). In plants, pattern recognition receptors (PRRs) described to date are all membrane-associated receptor-like kinases or receptor-like proteins, reflecting the prevalence of apoplastic colonization of plant-infecting microbes. An increasing inventory of elicitor-active patterns and PRRs indicates that a large number of them are limited to a certain range of plant groups/species, pointing to dynamic and convergent evolution of pattern recognition specificities. In addition to common molecular principles of PRR signaling, recent studies have revealed substantial diversification between PRRs in their functions and regulatory mechanisms. This serves to confer robustness and plasticity to the whole PTI system in natural infections, wherein different PRRs are simultaneously engaged and faced with microbial assaults. We review the functional significance and molecular basis of PRRmediated pathogen recognition and disease resistance, and also an emerging role for PRRs in homeostatic association with beneficial or commensal microbes.

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Section: Recognition Of Host Cell Alterations (Damps)mentioning

confidence: 99%

Pattern recognition receptors and signaling in plant–microbe interactions

2018

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“…These cell walldegrading enzymes promote the release of cell wall fragments, known as oligogalacturonides (OGs), which act as DAMPs and activate PTI (Kohorn et al, 2009;Brutus et al, 2010;Ferrari et al, 2013). Recently, oligomers derived from cellulose, such as cellobiose, have been shown to function as DAMPs and to activate defense responses in Arabidopsis (Souza et al, 2017). These cellobiose-induced responses are BAK1-independent and do not stimulate ROS bursts or callose deposition.…”

Section: Cell Wall: Building a Physical Barriermentioning

confidence: 99%

“…These cellobiose-induced responses are BAK1-independent and do not stimulate ROS bursts or callose deposition. Unlike other PAMPs/ DAMPs, cellobiose treatment increases seedling growth (Souza et al, 2017). Interestingly, co-treatment with cellobiose and other PAMPs/DAMPs leads to enhanced PTI responses, suggesting that plants perceive multiple PAMPs/DAMPs simultaneously to activate PTI responses to pathogen infection (Souza et al, 2017).…”

Section: Cell Wall: Building a Physical Barriermentioning

confidence: 99%

“…Unlike other PAMPs/ DAMPs, cellobiose treatment increases seedling growth (Souza et al, 2017). Interestingly, co-treatment with cellobiose and other PAMPs/DAMPs leads to enhanced PTI responses, suggesting that plants perceive multiple PAMPs/DAMPs simultaneously to activate PTI responses to pathogen infection (Souza et al, 2017). The identification of the PRR(s) that recognize cellulose oligomers should provide insight into the signaling pathways involved in the perception of these DAMPs.…”

Section: Cell Wall: Building a Physical Barriermentioning

confidence: 99%

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Plant–microbe interactions: organelles and the cytoskeleton in action

et al. 2017

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Contents Summary1012I.Introduction1012II.The endomembrane system in plant–microbe interactions1013III.The cytoskeleton in plant–microbe interactions1017IV.Organelles in plant–microbe interactions1019V.Inter‐organellar communication in plant–microbe interactions1022VI.Conclusions and prospects1023Acknowledgements1024References1024 Summary Plants have evolved a multilayered immune system with well‐orchestrated defense strategies against pathogen attack. Multiple immune signaling pathways, coordinated by several subcellular compartments and interactions between these compartments, play important roles in a successful immune response. Pathogens use various strategies to either directly attack the plant's immune system or to indirectly manipulate the physiological status of the plant to inhibit an immune response. Microscopy‐based approaches have allowed the direct visualization of membrane trafficking events, cytoskeleton reorganization, subcellular dynamics and inter‐organellar communication during the immune response. Here, we discuss the contributions of organelles and the cytoskeleton to the plant's defense response against microbial pathogens, as well as the mechanisms used by pathogens to target these compartments to overcome the plant's defense barrier.

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“…For example, cellulose‐derived oligomers including cellobiose induce several defense responses and may play a role in CWI surveillance. However, unlike OGs, cellobiose does not elicit a detectable ROS production and callose deposition (Aziz et al ., ; Souza et al ., ). Also cellotriose has been recently shown to induce a moderate defense‐like response, including the production of ROS, changes in membrane potential and expression of genes involved in defense and regulation of growth and root development (Johnson et al ., ; Oelmuller, ).…”

Section: Immunitymentioning

confidence: 97%

Cell wall traits that influence plant development, immunity, and bioconversion

et al. 2019

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Summary The architecture of the plant cell wall is highly dynamic, being substantially re‐modeled during growth and development. Cell walls determine the size and shape of cells and contribute to the functional specialization of tissues and organs. Beyond the physiological dynamics, the wall structure undergoes changes upon biotic or abiotic stresses. In this review several cell wall traits, mainly related to pectin, one of the major matrix components, will be discussed in relation to plant development, immunity and industrial bioconversion of biomass, especially for energy production. Plant cell walls are a source of oligosaccharide fragments with a signaling function for both development and immunity. Sensing cell wall damage, sometimes through the perception of released damage‐associated molecular patterns (DAMPs), is crucial for some developmental and immunity responses. Methodological advances that are expected to deepen our knowledge of cell wall (CW) biology will also be presented.

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Cellulose-Derived Oligomers Act as Damage-Associated Molecular Patterns and Trigger Defense-Like Responses

Cited by 215 publications

References 112 publications

Pattern recognition receptors and signaling in plant–microbe interactions

Pattern recognition receptors and signaling in plant–microbe interactions

Plant–microbe interactions: organelles and the cytoskeleton in action

Cell wall traits that influence plant development, immunity, and bioconversion

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