“…The formation of the hydrogel was therefore complete. These results are similar to those of a previous study by Ooi et al [16].Fig. 8Swelling ratios of gelatin and bacterial cellulose hydrogel composites.…”
“…The formation of the hydrogel was therefore complete. These results are similar to those of a previous study by Ooi et al [16].Fig. 8Swelling ratios of gelatin and bacterial cellulose hydrogel composites.…”
“…Drug carrying property of CNC-Gt hydrogels are examined with theophylline used as a model drug. Among the various preparations of CNC-Gt hydrogels with different ratios, 15% CNC reinforced Gt hydrogels were proved as the best potential candidate for controlled drug delivery system [53]. Another study was carried out about the preparation of Gt-poly (lactic-co-glycolic acid) (PLGA) and aminolated PLGA hydrogels for the drug delivery of hydrophobic drugs.…”
Section: Biomedical Application Model Drug Used Types Of Hydrogels Rementioning
Design and synthesis of well-ordered drug delivery systems are very important for medicinal and pharmaceutical and health care. Innovations of materials through nanotechnology and hydrogels have synergistically energized the growth of drug delivery. Uniqueness in material chemistry permits the creation of environmentally approachable, biocompatible, biodegradable and targeted drug delivery system. Large numbers of biopolymers have been examined for the design of drug delivery systems. Structure, size, shape and multi-functionality of drug delivery system can be controlled by the nanotechnology combined with biopolymer. Hydrogels have also been investigated as smart delivery systems capable to release, at the appropriate time and site of action, entrapped drugs in response to specific physiological triggers. This review mainly focuses on drug delivery applications of nanoparticles modified biopolymers and effective drug delivery system of biopolymer network based on hydrogels.
“…Recently, CNCs are anchored in the preparation of self‐healing nanocomposite hydrogels,65,66 which can effectively improve the service life and broaden the application range. CNCs‐based biomass hydrogels are widely used in controlled drug release,67 dye adsorption, and soft tissue engineering. With the strain‐sensitive properties, these self‐healing nanocomposite hydrogels are excellent candidates for wearable flexible sensors,68,69 enabling comprehensive detection of human motion.…”
Section: Introductionmentioning
confidence: 99%
“…[63,64] Recently, CNCs are anchored in the preparation of self-healing nanocomposite hydrogels, [65,66] which can effectively improve the service life and broaden the application range. CNCs-based biomass hydrogels are widely used in controlled drug release, [67] dye adsorption, and softIn the progress of red-winemaking, eco-friendly, facile, and efficient reutilization of grape pomace is an important issue for sustainable industrial processes. In this manuscript, cellulose nanocrystals (CNCs) as extensive and expensive nanomaterials, are efficiently extracted from grape pomace by using deep eutectic solvents.…”
In the progress of red‐winemaking, eco‐friendly, facile, and efficient reutilization of grape pomace is an important issue for sustainable industrial processes. In this manuscript, cellulose nanocrystals (CNCs) as extensive and expensive nanomaterials, are efficiently extracted from grape pomace by using deep eutectic solvents. Moreover, the obtained CNCs as the renewable reinforcing agent are successfully fabricated of self‐healing nanocomposite hydrogels. The self‐healing (93.5%) and mechanical strength (4.77 MPa) in hydrogels are outstandingly improved by the addition of functional CNCs, in which abundant carboxyl functional groups are modified by in situ esterification in the process of extracting CNCs. Importantly, these strain‐sensitive and self‐healing nanocomposite hydrogels can be further used as flexible strain sensors to detect human motion.
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