Cemented Total Knee Replacement in 24 Dogs: Surgical Technique, Clinical Results, and Complications

Allen, Matthew J.; Leone, Kendall A.; Lamonte, Kimberly; Townsend, Katy L.; Mann, Kenneth A.

doi:10.1111/j.1532-950x.2009.00528.x

Cited by 28 publications

(30 citation statements)

References 35 publications

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“…The measurement of thigh circumference using a tape measure has been reported in several studies [7,9,22,23]. Our results show that even the subjective evaluation of asymmetry in thigh muscle mass is a sensitive method for detecting functional problems.…”

Section: Discussionsupporting

confidence: 63%

Ranking of physiotherapeutic evaluation methods as outcome measures of stifle functionality in dogs

Hyytiäinen

Mölsä

Junnila³

et al. 2013

Acta Vet Scand

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BackgroundVarious physiotherapeutic evaluation methods are used to assess the functionality of dogs with stifle problems. Neither validity nor sensitivity of these methods has been investigated. This study aimed to determine the most valid and sensitive physiotherapeutic evaluation methods for assessing functional capacity in hind limbs of dogs with stifle problems and to serve as a basis for developing an indexed test for these dogs. A group of 43 dogs with unilateral surgically treated cranial cruciate ligament deficiency and osteoarthritic findings was used to test different physiotherapeutic evaluation methods. Twenty-one healthy dogs served as the control group and were used to determine normal variation in static weight bearing and range of motion.The protocol consisted of 14 different evaluation methods: visual evaluation of lameness, visual evaluation of diagonal movement, visual evaluation of functional active range of motion and difference in thrust of hind limbs via functional tests (sit-to-move and lie-to-move), movement in stairs, evaluation of hind limb muscle atrophy, manual evaluation of hind limb static weight bearing, quantitative measurement of static weight bearing of hind limbs with bathroom scales, and passive range of motion of hind limb stifle (flexion and extension) and tarsal (flexion and extension) joints using a universal goniometer. The results were compared with those from an orthopaedic examination, force plate analysis, radiographic evaluation, and a conclusive assessment. Congruity of the methods was assessed with a combination of three statistical approaches (Fisher’s exact test and two differently calculated proportions of agreeing observations), and the components were ranked from best to worst. Sensitivities of all of the physiotherapeutic evaluation methods against each standard were calculated.ResultsEvaluation of asymmetry in a sitting and lying position, assessment of muscle atrophy, manual and measured static weight bearing, and measurement of stifle passive range of motion were the most valid and sensitive physiotherapeutic evaluation methods.ConclusionsRanking of the various physiotherapeutic evaluation methods was accomplished. Several of these methods can be considered valid and sensitive when examining the functionality of dogs with stifle problems.

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Section: Discussionsupporting

confidence: 63%

Ranking of physiotherapeutic evaluation methods as outcome measures of stifle functionality in dogs

Hyytiäinen

Mölsä

Junnila³

et al. 2013

Acta Vet Scand

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“…The most common method that has been used in both species to determine regeneration capacity has been neuromorphometric analysis. Walking track analysis after orthopedic procedures has been described to measure improvement of motor function in dogs [35–37]. Dogs may be successfully trained for motor and sensory functional analyses.…”

Section: Discussionmentioning

confidence: 99%

A systematic review of animal models used to study nerve regeneration in tissue-engineered scaffolds

et al. 2012

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Research on biomaterial nerve scaffolds has been carried out for 50 years. Only three materials (collagen, polycaprolactone and polyglycollic acid) have progressed to clinical use. Pre-clinical animal models are critical for testing nerve scaffolds prior to implementation in clinical practice. We have conducted a systematic review of 416 reports in which animal models were used for evaluation of nerve regeneration into synthetic conduits. A valid animal model of nerve regeneration requires it to reproduce the specific processes that take place in regeneration after human peripheral nerve injury. No distinct animal species meets all the requirements for an ideal animal model. Certain models are well suited for understanding regenerative neurobiology while others are better for pre-clinical evaluation of efficacy. The review identified that more than 70 synthetic materials were tested in eight species using 17 different nerves. Nerve gaps ranged from 1 to 90 mm. More than 20 types of assessment methodology were used with no standardization of methods between any of the publications. The review emphasizes the urgent need for standardization or rationalization of animal models and evaluation methods for studying nerve repair.

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“…There are a couple of methods that assess nerve regeneration in these animals, including neuromorphometric analysis and behavioral testing. It is also easy to check the sensory and motor neuron functions in these animals (Allen, Leone, Lamonte, Townsend, & Mann, ; Braden et al, ). However, there are some disadvantages regarding the use of these animals, including ethical issues, their being very popular and the fact that they cannot be easily used in in clinical practices, high cost of purchasing and caring, and complexity of mechanistic analysis due to lack of sufficient equipment (Angius et al, ).…”

Section: Animal Model For Nerve Regeneration Studymentioning

confidence: 99%

The advances in nerve tissue engineering: From fabrication of nerve conduit toin vivonerve regeneration assays

Jahromi

Razavi

Bakhtiari

2019

J Tissue Eng Regen Med

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Peripheral nerve damage is a common clinical complication of traumatic injury occurring after accident, tumorous outgrowth, or surgical side effects. Although the new methods and biomaterials have been improved recently, regeneration of peripheral nerve gaps is still a challenge. These injuries affect the quality of life of the patients negatively. In the recent years, many efforts have been made to develop innovative nerve tissue engineering approaches aiming to improve peripheral nerve treatment following nerve injuries. Herein, we will not only outline what we know about the peripheral nerve regeneration but also offer our insight regarding the types of nerve conduits, their fabrication process, and factors associated with conduits as well as types of animal and nerve models for evaluating conduit function. Finally, nerve regeneration in a rat sciatic nerve injury model by nerve conduits has been considered, and the main aspects that may affect the preclinical outcome have been discussed.

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Cemented Total Knee Replacement in 24 Dogs: Surgical Technique, Clinical Results, and Complications

Abstract: Cemented TKR yields adequate clinical function and stifle joint excursion in the dog. Clinical studies are needed to determine the long-term fate of cemented TKR implants, to assess the influence of implant design on implant fixation and wear, and to obtain objective functional data.

Cited by 28 publications

References 35 publications

Ranking of physiotherapeutic evaluation methods as outcome measures of stifle functionality in dogs

Ranking of physiotherapeutic evaluation methods as outcome measures of stifle functionality in dogs

A systematic review of animal models used to study nerve regeneration in tissue-engineered scaffolds

The advances in nerve tissue engineering: From fabrication of nerve conduit toin vivonerve regeneration assays

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