Cementless total knee arthroplasty in ochronotic arthropathy

Aydoğdu, Semih; Çullu, Emre; Özsoy, Mustafa; Sur, Hakki

doi:10.1054/arth.2000.4228

Cited by 48 publications

(32 citation statements)

References 4 publications

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“…[11] In ochronotic arthropathy, it is not possible to compare the results of the arthroplasty with the results of other metabolic, degenerative or inflammatory diseases. [8] For this reason, our experience is severely limited. The solution is to perform a critical review of the literature.…”

Section: Discussionmentioning

confidence: 99%

“…Konttinen et al [7] performed cementless type arthroplasty for the quality of bone was considered good. Additionally, Aydoğdu et al [8] observed that there is never any pigment associated with bone tissue itself and the bone tissue is relatively protected from the disease process and implanted cementless prosthesis, because one could expect normal bone mechanism cement-free fixation.…”

Section: Discussionmentioning

confidence: 99%

“…Only Aydoğdu et al [8] reported pre-and postoperative knee scores. So it is not clear how the other authors achieved good or excellent outcomes.…”

Section: Discussionmentioning

confidence: 99%

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Okronoziste total diz artroplastisi: Olgu sunumu ve kritik literatür incelemesi

Özmanevra

Güran

Karatosun

et al. 2013

Eklem Hastalik Cerrahisi

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Okronoziste total diz artroplastisi: Olgu sunumu ve kritik literatür incelemesi

Özmanevra

Güran

Karatosun

et al. 2013

Eklem Hastalik Cerrahisi

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“…The spine and major weight-bearing joints are most commonly affected and symptoms usually start by the fourth decade. [5][6][7] In ochronotic spondylosis, although the entire spine is affected, symptoms are mainly related to the lumbar region.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous tendon ruptures in alkaptonuria

Kumar

Rajasekaran

2003

The Journal of Bone and Joint Surgery. British volume

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chronosis, the musculoskeletal manifestation of alkaptonuria, is known to lead to degenerative changes of the spine and weight-bearing joints. Symptoms related to degeneration of tendons or ligaments with spontaneous ruptures have not previously been reported. Three patients are described with four spontaneous ruptures of either the patellar tendon or tendo Achillis as the first symptom of alkaptonuria. Alkaptonuria is a rare autosomal recessive metabolic disorder due to deficiency of the enzyme homogentisic acid oxidase which is involved in the metabolism of homogentisic acid, a metabolic product of the aromatic amino acids phenylalanine and tyrosine.1 The homogentisic acid which accumulates is polymerised to form a dark pigment which is deposited in connective tissues. The pigment is also selectively deposited in the hyaline cartilage of major peripheral joints and intervertebral discs leading to early degeneration and arthritis. Apart from pigmentation of the skin, sclera and the pinnae, systemic symptoms related to the genitourinary, cardiovascular and respiratory systems have also been described. 2 The musculoskeletal manifestation of alkaptonuria is called 'ochronosis', a term which was coined by Virchow because of the ochre or yellow appearance of the cartilage under the microscope. By the fourth or fifth decade the disease usually progresses from simple alkaptonuria to alkaptonuric arthropathy in approximately 30% of subjects. While degenerative changes of the spine and major joints have been frequently reported, [2][3][4] there is no report of spon-

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“…Alkaptonuria affects mostly the knee joint followed by the hip as major weight bearing joints (7,8). Arthroscopic debridement and drilling may be helpful in the early stage of ochronitic arthropathy, but most of the patients will eventually require joint replacement (9).…”

Section: Introductionmentioning

confidence: 99%

Severe Osteoarthritis of the Knee as an Early Symptom of Alkaptonuria: A Case Report

Franz

Abusafieh

2016

Shafa Ortho J

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Introduction: Alkaptonuria (AKU) is a very rare disease and occurs due to the deficiency of the enzyme homogentisate1, 2-dioxygenase (HGD) which results in ochronosis, a term used to describe the dark pigmentation of the tissues. Alkaptonuria affects mostly the knee joint followed by the hip as major weight bearing joints, where the life quality of such patients is severely affected. Case Presentation: We present a case of Caucasian male who was suffering from severe osteoarthritis of the knee. Initially he underwent an arthroscopic partial meniscectomy in a nearby hospital. Fourteen months later we performed a total knee replacement using the Journey II CR prosthesis. We found a dark pigmentation of the inside of the knee (synovial tissue and cartilage). A positive urine test and a pathological specimen examination revealed the diagnosis of AKU. The patient had no complications after the surgery and underwent a standard rehabilitation program. Conclusions: Osteoarthritis could be the first manifestation of patients with AKU and the onset of the joint disease could be late and rapid.

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Cementless total knee arthroplasty in ochronotic arthropathy

Cited by 48 publications

References 4 publications

Okronoziste total diz artroplastisi: Olgu sunumu ve kritik literatür incelemesi

Okronoziste total diz artroplastisi: Olgu sunumu ve kritik literatür incelemesi

Spontaneous tendon ruptures in alkaptonuria

Severe Osteoarthritis of the Knee as an Early Symptom of Alkaptonuria: A Case Report

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