Central Auditory Processing Tests as Diagnostic Tools for the Early Identification of Elderly Individuals with Mild Cognitive Impairment

Jalaei, Bahram; Valadbeigi, Ayub; Panahi, Rasool; Nahrani, Morteza Hamidi; Arefi, Hossein Namvar; Zia, Maryam; Ranjbar, Nastaran

doi:10.7874/jao.2018.00283

Cited by 11 publications

(9 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…discussion), as speech-in-noise processing requires more than simply detecting quiet sounds. A number of studies directly assessing speech-in-noise ability have suggested a relationship with cognitive performance or with the development of dementia (H€ aggströ m et al, 2020;Jalaei et al, 2019;Mamo et al, 2019;Nixon et al, 2019;Pronk et al, 2019). However, the ability to make clear causal claims is problematic because speech-innoise ability requires a host of cognitive processes-auditory attention and grouping, word recognition, sentence processing, and sometimes speech production-that may themselves be affected by dementia.…”

Section: Mechanism 2: Impoverished Environment Causing Decreased Cognitive Reservementioning

confidence: 99%

How Can Hearing Loss Cause Dementia?

Griffiths

Lad

Kumar

et al. 2020

Neuron

233

220

View full text Add to dashboard Cite

Epidemiological studies identify midlife hearing loss as an independent risk factor for dementia, estimated to account for 9% of cases. We evaluate candidate brain bases for this relationship. These bases include a common pathology affecting the ascending auditory pathway and multimodal cortex, depletion of cognitive reserve due to an impoverished listening environment, and the occupation of cognitive resources when listening in difficult conditions. We also put forward an alternate mechanism, drawing on new insights into the role of the medial temporal lobe in auditory cognition. In particular, we consider how aberrant activity in the service of auditory pattern analysis, working memory, and object processing may interact with dementia pathology in people with hearing loss. We highlight how the effect of hearing interventions on dementia depends on the specific mechanism and suggest avenues for work at the molecular, neuronal, and systems levels to pin this down.

show abstract

Section: Mechanism 2: Impoverished Environment Causing Decreased Cognitive Reservementioning

confidence: 99%

How Can Hearing Loss Cause Dementia?

Griffiths

Lad

Kumar

et al. 2020

Neuron

233

220

View full text Add to dashboard Cite

show abstract

“…Temporal auditory processing assessments have been proposed to involve and reflect cognitive functions, such as attentive executive function and memory, as they involve information integration from both hemispheres across the corpus callosum in order to identify and process sequences of auditory patterns [168,181,182]. Additionally, diminished speech perception in noise, as tested using synthetic sentence identification-ipsilateral competing message (SSI-ICM) and speech perception in noise test (SPIN), has also been associated with cognitive impairment [170,173,183] [199,200]. However, other studies report no differences in ABR measures in people with AD [201,202] or MCI [203] in comparison to healthy age-matched controls.…”

Section: ) Occupation Of Cognitive Resources Mechanismmentioning

confidence: 99%

Understanding the Relationship Between Age-Related Hearing Loss and Alzheimer’s Disease: A Narrative Review

Tarawneh

Jayakody

Sohrabi

et al. 2022

Journal of Alzheimer's Disease Reports

View full text Add to dashboard Cite

Evidence suggests that hearing loss (HL), even at mild levels, increases the long-term risk of cognitive decline and incident dementia. Hearing loss is one of the modifiable risk factors for dementia, with approximately 4 million of the 50 million cases of dementia worldwide possibly attributed to untreated HL. This paper describes four possible mechanisms that have been suggested for the relationship between age-related hearing loss (ARHL) and Alzheimer’s disease (AD), which is the most common form of dementia. The first mechanism suggests mitochondrial dysfunction and altered signal pathways due to aging as a possible link between ARHL and AD. The second mechanism proposes that sensory degradation in hearing impaired people could explain the relationship between ARHL and AD. The occupation of cognitive resource (third) mechanism indicates that the association between ARHL and AD is a result of increased cognitive processing that is required to compensate for the degraded sensory input. The fourth mechanism is an expansion of the third mechanism, i.e., the function and structure interaction involves both cognitive resource occupation (neural activity) and AD pathology as the link between ARHL and AD. Exploring the specific mechanisms that provide the link between ARHL and AD has the potential to lead to innovative ideas for the diagnosis, prevention, and/or treatment of AD. This paper also provides insight into the current evidence for the use of hearing treatments as a possible treatment/prevention for AD, and if auditory assessments could provide an avenue for early detection of cognitive impairment associated with AD.

show abstract

“…They found poorer performance for listeners with MCI and AD compared to neurologically healthy age-and hearingmatched controls, consistent with our results. Other studies, however, have reported decrements in speech perception for adults with cognitive difficulties emerging only after the introduction of background noise (Jalaei et al, 2019;Lee, Park, Kim, & Kim, 2018).…”

Section: Discussionmentioning

confidence: 89%

Spoken Word Recognition in Listeners with Mild Dementia Symptoms

McClannahan

Mainardi

Luor

et al. 2022

JAD

View full text Add to dashboard Cite

Background: Difficulty understanding speech is a common complaint of older adults. In quiet, speech perception is often assumed to be relatively automatic. However, higher-level cognitive processes play a key role in successful communication in noise. Limited cognitive resources in adults with dementia may therefore hamper word recognition. Objective: The goal of this study was to determine the impact of mild dementia on spoken word recognition in quiet and noise. Methods: Participants were 53–86 years with (n = 16) or without (n = 32) dementia symptoms as classified by the Clinical Dementia Rating scale. Participants performed a word identification task with two levels of word difficulty (few and many similar sounding words) in quiet and in noise at two signal-to-noise ratios, +6 and +3 dB. Our hypothesis was that listeners with mild dementia symptoms would have more difficulty with speech perception in noise under conditions that tax cognitive resources. Results: Listeners with mild dementia symptoms had poorer task accuracy in both quiet and noise, which held after accounting for differences in age and hearing level. Notably, even in quiet, adults with dementia symptoms correctly identified words only about 80% of the time. However, word difficulty was not a factor in task performance for either group. Conclusion: These results affirm the difficulty that listeners with mild dementia may have with spoken word recognition, both in quiet and in background noise, consistent with a role of cognitive resources in spoken word identification.

show abstract

Central Auditory Processing Tests as Diagnostic Tools for the Early Identification of Elderly Individuals with Mild Cognitive Impairment

Cited by 11 publications

References 28 publications

How Can Hearing Loss Cause Dementia?

How Can Hearing Loss Cause Dementia?

Understanding the Relationship Between Age-Related Hearing Loss and Alzheimer’s Disease: A Narrative Review

Spoken Word Recognition in Listeners with Mild Dementia Symptoms

Contact Info

Product

Resources

About