Central giant cell granuloma of the maxilla: a case re-port

Abstract

Introduction: Central giant-cell is a benign lesion that predominantly involves the bone of the mandible and maxilla with a wide variation of its behavior. Surgery usually is the first choice in treatment of central giant cell granuloma. Case Report: In this case report we present a 29 years-old female with well define swelling on left maxilla. Diagnosis through incisional biopsy showed a central giant cell granuloma. Surgery with curettage was our treatment option with a follow up( 2 years ), No recurrence was reported. Discussion: Information on the maxillary central giant cell granuloma in published studies is insufficient. So here we present our case as unusual case presentation. Differential diagnosis of this case included osteosarcoma (parosteal type) since the tumor clinical presentation in periosteous tissue adjacent to the bone cortex and showed rapid growth. We chose the conventional surgical treatment by simple surgical curettage by mid-face degloving approach to avoid any facial scaring.

Granuloma central a células gigantes agresivo, de presentación atípica: reporte de un caso

“…El granuloma de central a células gigantes (GCCG) se clasifica como una lesión ósea benigna de los maxilares, aunque es localmente agresivo (1) . De etiología no definida, fue descrito por primera vez por Jaffe en 1953 (2) . EL GCCG es más frecuente en mujeres con proporción 2:1 (3,4) , en menores de 20 años (1,5) , con una proporción 2:3 en maxilar con respecto a mandíbula (6) .…”

“…EL GCCG es más frecuente en mujeres con proporción 2:1 (3,4) , en menores de 20 años (1,5) , con una proporción 2:3 en maxilar con respecto a mandíbula (6) . El GCCG es indoloro y de crecimiento lento, por lo que suele ser un hallazgo imagenológico (2) . Radiográficamente, el GCCG se presenta como una lesión radiolúcida solitaria, de aspecto quístico, y a medida aumenta de tamaño puede convertirse en una lesión multilocular (3) .…”

Assessment of Vascular Density, Myofibroblastic Activity and Cellular Cannibalism in Aggressive versus Non-Aggressive Central Giant Cell Granuloma of the Jaws

“…Recurrence was also reported in some of the aggressive cases. (2,3) Histopathologically lesions contain the stromal proliferation of fibroblasts and myofibroblasts, inflammatory cells, MNGCs, bone trabeculae and areas of hemorrhage may be present in several lesions. (3) Cellular cannibalism is known incident of engulfment of a living cell to another living cell leading to its death "the internalized one".…”