Central motor conduction studies in patients with spinal cord disorders: a review

Diagnostic transcranial magnetic stimulation as a prognostic tool in children with acute transverse myelitis

“…When motor responses to TMS are seen after it, this finding is considered to be suggestive of 'root sparing' as a basis for motor function. 3,4 As may be suggested from the correlation between MEP absence in our group of patients who did not show clinical recovery in the follow-up period and vice versa in those who recovered sufficiently, TMS in this population can identify residual pathways not apparent from clinical assessment alone. This may have a prescriptive value for rehabilitation.…”

“…6 TMS can detect corticospinal tract abnormalities not identified by neuroimaging. 3,4,6 In the patients with compressive myelopathies, TMS was found to be helpful in determining the functional significance of neuroimaging findings. TMS can supplement clinical examination and neuroimaging findings also in the assessment of the spinal cord injury level.…”

“…TMS can supplement clinical examination and neuroimaging findings also in the assessment of the spinal cord injury level. 3,4 However, reports of TMS use in pediatric acute myelitis are relatively rare, and mostly such works are case reports or small series consisting of 2-3 patients. 7 We have performed the investigation of corticospinal pathway characteristics in children with acute myelitis, with special attention toward clinical significance of TMS and its prognostic value in this case.…”

“…2 Clinical examination in children is sometimes unreliable, and standard neurophysiologic tests could be insufficient in setting precise diagnosis; thus, transcranial magnetic stimulation (TMS) is considered as one of the valuable diagnostic methods. 3,4 TMS is a method for focal noninvasive brain stimulation that is based on the principles of electromagnetic induction. 5 TMS is an effective diagnostic and a therapeutic technique with applications in neurology, psychiatry and rehabilitation medicine, which can provide insight into developmental neurology and neurophysiology in children.…”

Benefits of Early Treatment for Patients with Hepatic Myelopathy Secondary to TIPS: A Retrospective Study in Northern China

“…Possibly, circulatory shunting allows byproducts of nitrogenous degradation or a potential neurotoxin to escape hepatic detoxification, causing damage to the spinal cord. Interestingly, Nardone 13 found that motor evoked potentials (MEP) in patients with more advanced disease were not substantially altered by LT, whereas LT conferred notable neurophysiologic and clinical benefit in patients with early stages of HM. Such findings suggest that HM may be reversible if treated early and timely, perhaps avoiding liver transplantation.…”