Central odontogenic fibroma, granular cell variant

Reichart, Peter A.; Philipsen, H. P.; Moegelin, A; Thalmann, U.

doi:10.1016/j.ooe.2005.05.007

Cited by 19 publications

(21 citation statements)

References 9 publications

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“…The term ‘ central granular cell odontogenic fibroma’ was also used in the literature , considering it as a histologic variant of odontogenic fibroma with the origin of the GCs from odontogenic mesenchyme or odontogenic mesenchymal fibroblasts . Average age of the patients (44.56 years) and presence of OE without stellate reticulum lend support to the tumor being a variant of central odontogenic fibroma.…”

Section: Nomenclaturementioning

confidence: 99%

“…Reichart et al. reported a case which they term ‘ central odontogenic fibroma of the epithelium‐rich type (granular cell variant)’ . It was stated that, occasionally, the GCs comprise a conspicuous cell component and the underlying odontogenic tumor in which the GCs have developed is ignored.…”

Section: Nomenclaturementioning

confidence: 99%

“…Central granular cell odontogenic tumor is an extraordinarily rare condition. Only 38 cases have been reported in the literature till date . The aim of the present review article is to comprehensively review the nomenclature, clinical, radiological, histopathological, histogenetic, and treatment aspects of the CGCOT published in the English medical literature.…”

Section: Introductionmentioning

confidence: 99%

“…Reference lists from the citations were also reviewed for the relevant publications. A total of 37 papers were obtained from the initial search . The case reports or case series with confirmed histopathological diagnosis of CGCOT or histopathological features suggestive of CGCOT but reported with other terminologies (mentioned in the nomenclature) were identified.…”

Section: Introductionmentioning

confidence: 99%

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Central granular cell odontogenic tumor: a systematic review

Sarode

Vaidya

2013

J Oral Pathology Medicine

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Central granular cell odontogenic tumor (CGCOT) is a rare benign odontogenic neoplasm reported with various terms and is not included in the 2005 WHO classification of odontogenic tumors. It shows a predilection for middle-aged women, usually presenting as an asymptomatic swelling of the mandibular premolar-molar region. Radiographic manifestations include unilocular or multilocular radiolucent lesion, but mixed density lesions can also occur. Histopathology shows sheets and lobules of round to polygonal cells with abundant eosinophilic, granular cytoplasm and eccentrically placed nuclei. Immunohistochemical and ultrastructural features suggest the histiocytic origin of granular cells. The neoplasm does not exhibit an aggressive biological behavior and hence enucleation or curettage ensuring complete removal remains the treatment of choice. We present a systematic review on clinical, radiological, histopathological, immunohistochemical and treatment aspect of CGCOT. Published articles were identified through a literature search using online databases (PubMed, MED-LINE, Scopus) and cross-references for papers published from the year 1950 to March 2013. From a total of 37 papers, 26 (38 cases) were extracted from the database for systematic review.

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Section: Nomenclaturementioning

confidence: 99%

Section: Nomenclaturementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Central granular cell odontogenic tumor: a systematic review

Sarode

Vaidya

2013

J Oral Pathology Medicine

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“…Odontogenic fibroma (OF) is a very rare neoplasm that only develops in the maxilla and mandible [1]. According to the WHO classification adopted in 2005, there are two types of odontogenic fibroma: epithelium-poor and epithelium-rich [2].…”

Section: Case Reportmentioning

confidence: 99%