Central Serous Chorioretinopathy and Helicobacter Pylori

Abstract

The results of this study show that the prevalence of H. pylori infection seems to be significantly higher in patients with CSC than in control s. H. pylori infection may represent a risk factor in patients with CSC.

Therapeutic benefit of melatonin in refractory central serous chorioretinopathy

“…Five patients with chronic CSCR served as a control group. The mean age of control patients was 44 years old (range, [34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53], with the woman/man ratio being 1 : 4. The number of right and left eyes studied was also similar (3 right eyes and 2 left eyes).…”

“…Several factors have been implicated in the initiation and development of this retinal disorder, including immunological reactions, toxins, infections, and neuronal, hormonal, or circulatory processes. [34][35][36][37][38] One theory suggests that there is a focal increase in the choriocapillaris permeability that causes damage to the overlying RPE, and it is suspected that the disturbance would originate in an alteration of the mechanisms of choroidal blood flow autoregulation. 39 An alternative hypothesis postulates that CSCR is provoked by a dysfunction of the RPE that, in turn, causes a reverse in fluid movement in a chorioretinal direction, leading to subretinal space leakage and retinal detachment.…”

Review and update for central serous chorioretinopathy

“…In addition, several investigators reported that the prevalence of Helicobacter pylori is high in patients with CSC [18].…”

Helicobacter pylori and Hematologic Diseases

“…At the moment, there are no new reports of this association in the medical literature possibly only because it is not being considered or investigated. However, it is worth recalling that antiphospholipid syndrome has been associated with other diseases of immunologic origin that in turn are associated with H. pylori infection, such as ITP [189,219,220], systemic lupus erythematosus [221], and central serous chorioretinitis [222,223].…”