Central serous chorioretinopathy in coronavirus disease-19 patient

Abstract

A 46-year-old male with mild coronavirus disease 2019 (COVID-19) symptoms presented to the emergency department complaining of decreased vision in the right eye (RE). Funduscopic examination revealed serous macular detachment at the posterior pole with loss of foveal reflex in the RE. Fundus fluorescein angiography revealed pinpoint leakage in the early phase, which was enlarged in the late phase to appear like inkblot suggestive of central serous chorioretinopathy (CSCR), which was confirmed on optical coherence tomography as hyporeflective space due to the collection of serous fluid between the neurosensory retina and retinal pigment epithelium. He received COVID-19 directed therapy. The patient became systemically alright and his vision in the RE improved. Severe acute respiratory syndrome coronavirus 2 is associated with thromboembolic events and retinal ischemia may create hyperpermeability of choroid leading to the formation of CSCR.

Post COVID-19 Ocular Manifestations

“…As evidenced by binding with ACE2 receptors (RPE), an immunohistochemical investigation of human eyes revealed the cornea, sclera, choroid, ciliary body, retinal pigment epithelium and retina as the primary sites of contact between SARS-CoV-2 and host. The cytokine storm that the SARS virus produces damages the integrity of the vascular endothelium and results in ocular disorders by causing increased permeability, activated coagulation, and microcirculation abnormalities [12]. We reported that main post COVID-19 infection patient's complaint was pain, red eye, diminution of vision and itching in percentage of (37.5%,28.6%,18.2% and 14.3%) respectively.…”