Central Venous Oxygen Saturation Cannot Replace Mixed Venous Saturation in Patients Undergoing Cardiac Surgery

Diagnostic accuracy of central venous saturation in estimating mixed venous saturation is proportional to cardiac performance among cardiac surgical patients

“…Our data is in line with similar observations in diverse clinical settings [8,17,18,19]. We also specifically investigated the impact of the underlying hemodynamic status on the interchangeability of ScvO 2 and SvO 2 by dichotomizing patients based on a cardiac index cut-off point of 2.0 L/min/m 2 .…”

Agreement between Central and Mixed Venous Oxygen Saturation Following Cardiac Surgery

“…The lower SvO 2 -toScvO 2 gap with infusions like dobutamin and milrinon as compared to infusions like dopamine and adrenalin may be due to the different effect on splanchnic, renal and cardiac oxygen extraction. The type of surgery was also suggested as a factor that modulates the relation between SvO 2 and ScvO 2 [10]. Our results shows that the limits of agreement remained high and clinically unacceptable regardless the surgical procedure.…”

“…However, limits of agreement remained large and difficult to accept. On the contrary, Lorentzen et al [10] found that Patients receiving inotropic treatment had lower venous differences. Possible reason of different results was that they included only three patients on inotropes in their analysis.…”

“…Sander et al [14] concluded that after cardiac surgery; ScvO 2 >70% predicts adequate oxygen delivery. However, Lorenzten et al [10] suggested it might not be a reliable sign of adequate tissue oxygenation.…”

“…The previous studies evaluating the relationship between ScvO 2 and SvO 2 showed a significant variation in results because of different study designs and clinical setup which included intensive care patients with either sepsis, heart failure, or shock [4][5][6][7]. Studies involving such relationship during and after cardiac surgery [8][9][10][11][12][13][14][15] also showed contradicting results, this controversy is generating confusion among clinicians and further work is needed to explore this area.…”