Central Venous Oxygen Saturation in Shock

Lee, Joseph; Wright, Fred A.; Barber, Richard T.; Stanley, Lauren E.

doi:10.1097/00000542-197205000-00012

Cited by 157 publications

(58 citation statements)

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“…19,20 Reinhart et al 21 compared mixed venous saturation to saturation in the superior vena cava in an experimental model and demonstrated an excellent correlation (r = 0.97). Lee et al 22 studied 29 stable patients and 15 patients in circulatory shock (septic, hemorrhagic and neurogenic) and detected a good correlation between venous atrial and mixed saturation. In the present study, the use of atrial blood for calculation of venous oxygen content showed a good correlation with venous content, especially when we used a correction factor (r = 0.94).…”

Section: Figure 4 -mentioning

confidence: 96%

Indirect calorimetry can be used to measure cardiac output in septic patients?

et al. 2008

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Purpose: The aim of this study was to compare two different cardiac output (CO) monitoring systems based on the thermodilution principle (Thermo-CO) and indirect calorimetry (Fick mixed-CO) in septic patients. Methods: Prospective study in septic patients admitted in an intensive care unit of a university hospital. Nineteen patients aged on average 45.4 ± 21.5 years were enrolled in the study. Four series of hourly measurements by the two techniques were carried out simultaneously. Results: No significant differences were observed between Thermo-CO and Fick mixed-CO (7.0 ± 1.8 L.min -1 and 6.4 ± 1.7 L.min -1. ). Parallel analysis of Fick mixed-CO and Fick atrial-CO was performed introducing a correction factor for the eight atrial samples in order to adjust the values of oxygen saturation obtained from atrial blood (Fick corrected atrial-CO) to those obtained from mixed venous blood. No significant differences could be detected between Fick mixed-CO and Fick corrected atrial-CO. The correlation coefficients of Thermo CO/Fick mixed-CO and Fick mixed-CO/ Fick corrected atrial-CO were 0.84 and 0.94, respectively. Conclusion: We observed that the agreement between the two methods was satisfactory on the basis of the decisions made for treatment. Indirect calorimetry is useful to measure CO in patients with septic shock.Key words: Indirect Calorimetry. Cardiac Output. Septic Shock. Intensive Care Setting. RESUMOObjetivo: O objetivo deste estudo foi comparar as medidas do débito cardíaco (DC) obtidas pela termodiluição (DC-termo) e pela calorimetria indireta (DC-Fick misto) em pacientes com choque séptico. Métodos: Estudo prospectivo em pacientes sépticos internados em unidade de terapia intensiva de um hospital universitário. Foram estudados 19 pacientes (45,4 ± 21,5 anos). Foram realizadas quatro séries de medidas do DC pelos dois métodos, simultaneamente. Resultados: Não houve diferenças significativas entre os valores do DC-termo e DC-Fick misto (7,0 ± 1,8 L.min -1 e 6,4 ± 1,7 L.min -1 , respectivamente). Na avaliação dos oito casos (DC-Fick misto/DC Fick atrial), introduziu-se um fator de correção para aproximar os valores do conteúdo de O 2 atrial (DC-Fick atrial corrigido) com o venoso misto. Não houve diferença significativa do DC-Fick misto e DC-Fick atrial corrigido nos 4 tempos. A correlação foi de 0.84 para o DC-termo/DC-Fick misto e de 0.94 para o DC-Fick misto/DC-Fick atrial corrigido. Conclusão: A calorimetria indireta é um bom método para a medida do DC em pacientes vítimas de choque séptico, sobretudo nos casos onde a monitorização hemodinâmica invasiva não está disponível ou está contra indicada.

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Section: Figure 4 -mentioning

confidence: 96%

Indirect calorimetry can be used to measure cardiac output in septic patients?

et al. 2008

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“…In patients with a failing heart ScvO2 was slightly higher than SvO2 and in shock patients the difference between SvO2 to ScvO2 was even more expressed (47.5% ± 15.11% vs. 58.0% ± 13.05%, respectively, p<0.001). Lee and co-workers described similar findings (51). Other more detailed studies in mixed groups of critically-ill patients designed to test if the ScvO2 measurements could substitute the SvO2 showed problematically large confidence limits (52) and poor correlation between the two values (53).…”

Section: Nirs For Evaluation Of Skeletal Muscle Tissue Oxygenation Inmentioning

confidence: 59%

How I use skeletal muscle Near Infrared Spectroscopy to non-invasively assess hemodynamic status of the critically ill

Podbregar¹

2017

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The major goal of hemodynamic treatment is to reach adequate flow. Near infrared spectroscopy (NIRS) allows non-invasive assessment of skeletal muscle tissue oxygenation during rest and also during vascular occlusion test (VOT). VOT allows estimation of tissue oxygen extraction capability, which could be preserved (i.e. hypovolemic, obstructive and cardiogenic shock) or inappropriate (i.e. sepsis/ septic shock). By using ultrasound to estimate cardiac output, arterial hemoglobin oxygen saturation, skeletal muscle NIRS, arterial lactate and hemoglobin, therapeutic goals in critically ill patients with preserved oxygen extraction capability can easily be targeted. Current controversies of NIRS technology and approach to patients with impaired oxygen extraction are discussed as well.

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“…Consequently, ScvO 2 is usually less than SvO 2 mainly due to high oxygen content in renal venous drainage2, this relationship changes in sick patients with hemodynamic changes, oxygen extraction become higher in renal and splanchnic circulation resulting in reversal of SvO 2 -to-ScvO 2 relationship [19]. [20], this included critically ill ICU patients [21], and during liver transplantation [22].…”

Section: Discussionmentioning

confidence: 99%

Agreement between Central and Mixed Venous Oxygen Saturation Following Cardiac Surgery

Belghaith¹

2014

J Anesth Clin Res

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Central Venous Oxygen Saturation in Shock

Cited by 157 publications

References 0 publications

Indirect calorimetry can be used to measure cardiac output in septic patients?

Indirect calorimetry can be used to measure cardiac output in septic patients?

How I use skeletal muscle Near Infrared Spectroscopy to non-invasively assess hemodynamic status of the critically ill

Agreement between Central and Mixed Venous Oxygen Saturation Following Cardiac Surgery

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