Central venous oxygen saturation/lactate ratio: a novel predictor of outcome following emergency open laparotomy

Salem, G; Abbas, Nora; Zakaria, Ahmed; Radwan, Wahid Ahmed

doi:10.1007/s00068-019-01188-0

Cited by 2 publications

(3 citation statements)

References 18 publications

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“…A study conducted in the multidisciplinary intensive care unit showed that mortality in patients with ScvO2 below 60% was 1.7 times higher as compared to patients with higher values of this marker. Treatment attempts only resulted in a slight increase in ScvO2 which, however, did not affect the fatal outcome [14].…”

Section: Scvo2 Values Can Differ Considerably In Various Clinical Sitmentioning

confidence: 84%

“…A study conducted in a multidisciplinary intensive care unit showed that mortality in patients with ScvO 2 <60% was 1.7 times higher compared with patients with higher ScvO 2 values. Treatment attempts only resulted in a slight increase in ScvO 2 , and did not affect the fatal outcome ( Salem et al, 2019 ). Similar clinical findings were observed in the present study in deceased patients.…”

Section: Discussionmentioning

confidence: 99%

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Oxygen metabolism markers as predictors of mortality in severe COVID-19

Oliynyk¹,

Rorat²,

Barg³

2021

International Journal of Infectious Diseases

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Section: Scvo2 Values Can Differ Considerably In Various Clinical Sitmentioning

confidence: 84%

Section: Discussionmentioning

confidence: 99%

Oxygen metabolism markers as predictors of mortality in severe COVID-19

Oliynyk¹,

Rorat²,

Barg³

2021

International Journal of Infectious Diseases

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“…The critical values for ScvO 2 and lactate in these studies were 60-70% and 2-4 mmol/L, respectively [9][10][11]. Serial blood lactate levels and the ScvO2/lactate ratio are useful predictors of death within 7 days after laparotomy [12]. Rivers et al [13] used an increase in lactate levels to identify a subset of patients with severe sepsis and septic shock; this subset was treated early with medications aimed at improving ScvO2, and morbidity and mortality rates were reduced as a result.…”

Section: Introductionmentioning

confidence: 98%

Prognostic value of combined central venous oxygen saturation and lactate in pediatric patients after cardiac surgery

Abdelaziz,

ElGendy,

Hegazy

et al. 2023

Egypt Pediatric Association Gaz

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Objectives This study assessed the value of measuring both arterial lactate levels and central venous oxygen saturation (ScvO2) in predicting cardiac surgery outcomes in pediatric patients. Methods A prospective cohort study was conducted on 73 patients who underwent surgery for congenital heart disease. Vasoactive-inotropic score (VIS), serial mean arterial blood pressures (MAP), lactate levels, and ScvO2 were measured immediately and 3, 6, 12, 18, and 24 h after admission to the pediatric intensive care unit (PICU). To test the prognostic values of these markers, we calculated the areas under the receiver operating characteristic curves (AUCs). Binary logistic regression was used to identify the determinants of postsurgical complications. Results The most common complications after cardiac surgery were the prolonged need for mechanical ventilation (38.36%), chest infection (30.14%), prolonged stay in the PICU (24.66%), and sepsis (9.59%). ScvO2 6 h after admission was most predictive of complications (AUC = 85.5%), followed by ScvO2/lactate (AUC = 83.0%), lactate level 12 h after admission (AUC = 75.0%), MAP (AUC = 73.6%), and VIS (AUC = 63.4). In multivariate analysis, body weight and ScvO2 6 h after PICU admission were the main predictors of complications (OR = 0.01, 95% CI 0.001–0.689, p = 0.033), and (OR = 0.87, 95% CI 0.798–0.948, p = 0.002) respectively. Conclusions To predict complications after pediatric cardiac surgery, lactate measurement does not add value to ScvO2 measurement 6 h after admission. The Cochrane TRN PACTR202104905893217. Date of registration 12 April 2021.

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Central venous oxygen saturation/lactate ratio: a novel predictor of outcome following emergency open laparotomy

Cited by 2 publications

References 18 publications

Oxygen metabolism markers as predictors of mortality in severe COVID-19

Oxygen metabolism markers as predictors of mortality in severe COVID-19

Prognostic value of combined central venous oxygen saturation and lactate in pediatric patients after cardiac surgery

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