“…Currently, rather than dysfunctional patients, clinicians routinely face conditions requiring important occlusal modifications in otherwise functionally healthy subjects, typically in esthetic restorative cases, where extensive prosthetic reconstructions, orthodontic therapy, and complex surgical‐orthodontic treatments may be necessary to achieve the required esthetic goals (Figure 1). Regardless of the reasons why treatment has been decided (restoring tooth wear, replacing extensive tooth loss, periodontal breakdown, a combination of all the previous conditions or even just an improvement in esthetics required by the patient), there is a general consensus around the advantages to refer to some reference position starting from which the patient's occlusion can be reorganized after the maximal intercuspal position has been modified 1–7,13,14 . Indeed, in spite of decades of philosophical controversies, 3–5 in a clinical perspective the role of a maxillo‐mandibular relation change should be rather a practical than a biological goal 13,14 .…”