Cephalic kinetics of intra-arterially injected lidocaine

Aldrete, J. Antonio; Nicholson, John; Sada, Tsuneo; Davidson, William R.; Garrastasu, George

doi:10.1016/0030-4220(77)90263-8

Cited by 17 publications

(7 citation statements)

References 6 publications

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“…Aldrete and co-workers marshaled considerable evidence to support their “reverse carotid flow” theory. They found, for example, high concentrations of lidocaine in the internal carotid artery immediately after injecting the drug into the facial artery of dogs [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Status epilepticus following local anesthesia in a previously healthy adult

et al. 2016

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BackgroundLocal anesthesia could result in lethal complications if injected in highly vascularized area. Dentist should take care to avoid such complications.Case presentationWe present a case of 15 year old girl with a coma following convulsive status epilepticus which developed after inferior alveolar nerve blockade by a dentist. The patient was admitted to the intensive care unit ICU and recovered within several days.ConclusionThis case is reported to tell both of dentists and medical staff that although it is uncommon, such complications of local anesthesia should be in mind to be avoided and managed promptly if happened.

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Section: Discussionmentioning

confidence: 99%

Status epilepticus following local anesthesia in a previously healthy adult

et al. 2016

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“…It is unclear whether one of these organ systems or both were affected. However, it is tempting to suggest a retrograde arterial route to the brain to explain the rapid effect (11–13).…”

Section: Discussionmentioning

confidence: 99%

Unintentional hypotension from lidocaine infiltration during orthognathic surgery and general anaesthesia

Enlund¹,

Mentell²,

Krekmanov³

2001

Acta Anaesthesiol Scand

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“…In none of the published cases in which serum levels were reported did patients reach these thresholds [ 8 , 9 ]. It is thought that levels in the immediate region of localized spread are high enough to induce serious complications, while serum levels may reflect a more diluted concentration [ 10 ].…”

Section: Discussionmentioning

confidence: 99%

A Case of Brainstem Anesthesia after Retrobulbar Block for Globe Rupture Repair

Nanda

Ross

Kerr

2021

Case Reports in Anesthesiology

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Purpose. To present a rare case of brainstem anesthesia from retrobulbar block and discuss evidence-based methods for reducing the incidence of this complication. Case. A 72-year-old female, was given a retrobulbar block of 5 mL of bupivacaine 0.5% for postoperative pain management, after a globe rupture repair under general anesthesia. Prior to injection, the patient was breathing spontaneously via the anesthesia machine circuit and had not received any additional narcotics/muscle relaxants for 2.5 hr (with full recovery of neuromuscular blocking agent after anesthetic reversal). Over 7 min, however, there was a steady increase in ETCO2 and the patient became apneic, consistent with brainstem anesthesia. She remained intubated and was transported to the postanesthesia care unit for prolonged monitoring, with eventual extubation. Discussion. Brainstem anesthesia is an important complication to recognize as it can lead to apnea and death. The judicious use of anesthetic volume, shorter needle tips, and mixed formulations can help reduce the chance of brainstem anesthesia. Observation of the contralateral eye 5–10 minutes after injection for pupillary dilation, and prior to surgical draping, can help identify early CNS involvement.

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Cephalic kinetics of intra-arterially injected lidocaine

Cited by 17 publications

References 6 publications

Status epilepticus following local anesthesia in a previously healthy adult

Status epilepticus following local anesthesia in a previously healthy adult

Unintentional hypotension from lidocaine infiltration during orthognathic surgery and general anaesthesia

A Case of Brainstem Anesthesia after Retrobulbar Block for Globe Rupture Repair

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