Cephaloceles: Treatment, Outcome, and Antenatal Diagnosis

Simpson, Donald; David, David J.; White, J.

doi:10.1227/00006123-198407000-00005

Cited by 124 publications

(83 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…14 The condition is also found in India 19 and Australia in the aboriginal population. 35 This specific and unique geographical distribution of fMEC may provide clues in the investigation of its etiology, with respect to genetic/racial or environmental factors, although the matter is complicated by the occasional discovery of fMECs in ethnically diverse groups-for example, in various African countries, 6,17 Mexico, 9 and Turkey. 41 On the other hand, fMECs are rare in Western Europe, Japan, and North America, even in immigrants from Southeast Asia despite their presence in large minority groups.…”

Section: Geographical Distribution and Etiologymentioning

confidence: 99%

Frontoethmoidal meningoencephalocele: appraisal of 200 operated cases

Oucheng

Lauwers

Gollogly

et al. 2010

PED

View full text Add to dashboard Cite

Object Frontoethmoidal mengingoencephaloceles (fMECs) are frequently observed in Cambodia, especially in poor families. The authors describe issues related to the surgical treatment of fMECs in Cambodia at the end of a humanitarian program that provided surgery free of charge to patients and their families. Methods The authors reviewed 257 cases of fMEC involving patients who presented to their institution, the Children's Surgical Center in Phnom Penh, between 2004 and 2009. They treated 200 of these patients surgically (108 males, 92 females; 89% younger than 18 years) using a “low-cost” management plan with no routine pre- or postoperative investigations. Initially, surgery was performed by visiting foreign surgeons who taught the procedures to resident surgeons. Patients were not charged for consultations or treatment and received at least 1 follow-up examination 6 months postoperatively. Results The nasoethmoidal type was the most frequent fMEC encountered (69%). Many patients had associated ophthalmological issues (46% of cases). Only 1 familial case was detected. Combined neurosurgical and facial procedures were successfully standardized and learned by surgeons initially unfamiliar with fMEC management. A neurosurgical approach avoided the need for a facial incision in 42 cases, improving cosmetic results. The most common postoperative issues were a temporary CSF leak (24 cases [12%]) and/or infection (28 cases [14%]). There were 3 deaths directly related to the operations. Cosmetic results were good in 145 cases, average in 27, poor in 7, and worse than preoperative appearance in 6 patients. Fifteen patients were lost to follow-up. The parents of 87% of the children were rice farmers. Questionnaire results confirmed that fMEC has important social and educational consequences for the affected children and that these consequences can be partially improved by fMEC correction. Conclusions This experience in fMEC management demonstrates that local surgeons can treat these malformations with limited surgical materials and in a nonspecialized infrastructure after principles of treatment have been learned and if they are carefully respected. Surgery for fMEC can thus be more accessible to a larger number of patients in developing countries. Moreover, local treatment facilitates better postoperative and follow-up care.

show abstract

Section: Geographical Distribution and Etiologymentioning

confidence: 99%

Frontoethmoidal meningoencephalocele: appraisal of 200 operated cases

Oucheng

Lauwers

Gollogly

et al. 2010

PED

View full text Add to dashboard Cite

show abstract

“…[4,5] The frontoethmoidal type, which is the most common form, is observed in Thailand in every 5000-6000 births. Despite the high incidence in specific regions, very little is known about the etiology and pathogenesis of this disease, and often environmental factors are blamed as potential causes.…”

Section: Discussionmentioning

confidence: 99%

Prenatally Diagnosed Primary Frontoethmoidal Encephalocele: A Case Report

Kavak¹

2017

South Clin Ist Euras

View full text Add to dashboard Cite

“…6 There is no known genetic mutation present to explain the lesion, and higher incidence is in Southeast Asia (1:6000 live births), of that about 70% occur in females. 7 Prenatal diagnosis of encephalocoeles is done by ultrasonography, maternal serum Alfa-fetoprotein (MSAFP) and amniocentesis. 8,9 These lesions are mostly covered with normal, dysplastic skin or a thin, distorted meningeal membrane.…”

Section: Introductionmentioning

confidence: 99%