Ceramic membranes for separation of proteins and DNA through in situ growth of alumina nanofibres inside porous substrates

Ke, Xuebin; Shao, Renfu; Zhu, Hua; Yuan, Yong; Yang, Dong; Ratinac, Kyle; Gao, Xue

doi:10.1039/b819292h

Cited by 25 publications

(17 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is a consensus that surface properties of BSA vary across the molecule giving rise to charge heterogeneity (Baier et al, 2011), along with hydrophobic and hydrophilic regions (Yoon et al, 1998). Consequently, morphological models of BSA needs simplification to certain degrees: it is described either as a globular ellipsoid of about 14 x 3.8 x 3.8 nm (Ke et al, 2009;Togashi et al, 2009), a heart-shaped solid with three different domains (Voros, 2004), or a flexible foldable polymer (Chiku et al, 2008). Among them, the ellipsoid model not only provides explicit size and geometry description of the protein molecule, but also offers a realistic means to characterise the adsorbed conformation in end-on (long axis perpendicular to collector surface) or side-on (short axis perpendicular to collector surface) (Yoon et al, 2003;Schrott et al, 2009).…”

Section: Double Pulse Column Experiments (Dpes)mentioning

confidence: 99%

Modeling colloid deposition on a protein layer adsorbed to iron-oxide-coated sand

Yang

Flynn

Kammer

et al. 2012

Journal of Contaminant Hydrology

View full text Add to dashboard Cite

Our recent study reported that conformation change of granule-associated Bovine Serum Albumin (BSA) may influence the role of the protein controlling colloid deposition in porous media (Flynn et al., 2012). The present study conceptualized the observed phenomena with an ellipsoid morphology model, describing BSA as an ellipsoid taking a side-on or end-on A C C E P T E D M A N U S C R I P T ACCEPTED MANUSCRIPT5 conformation on granular surface, and identified the following processes: (1) at low adsorbed concentrations, BSA exhibited a side-on conformation blocking colloid deposition; (2) at high adsorbed concentrations, BSA adapted to an end-on conformation promoted colloid deposition; (3) colloid deposition on the BSA layer may progressively generate end-on molecules (sites) by conformation change of side-on BSA, resulting in sustained increasing deposition rates. Generally, the protein layer lowered colloid attenuation by the porous medium, suggesting the overall effect of BSA was inhibitory at the experimental time scale.A mathematical model was developed to interpret the ripening curves. Modelling analysis identified the site generation efficiency of colloid as a control on the ripening rate (declining rate in colloid concentrations), and this efficiency was higher for BSA adsorbed from a more dilute BSA solution.

show abstract

Section: Double Pulse Column Experiments (Dpes)mentioning

confidence: 99%

Modeling colloid deposition on a protein layer adsorbed to iron-oxide-coated sand

Yang

Flynn

Kammer

et al. 2012

Journal of Contaminant Hydrology

View full text Add to dashboard Cite

show abstract

“…Applications such as alumina membranes for juice processing [1], protein separation [2], and oil/water emulsion separation [3], titania membranes for wastewater processing [4], zirconia membranes for processing vegetable oil [5] and food [6], zeolites for the dehydration of organic solvents [7], cobalt silica membranes for ammonia separation from waste waters [8] and carbonized templated silica membranes for desalination [9] are some of many examples. Inorganic membranes have a very wide range of pore sizes from microfiltration to ultrafiltration to nanofiltration and even down to the sub-nanometer range depending on the materials of choice and synthesis conditions.…”

Section: Introductionmentioning

confidence: 99%

Vacuum-assisted tailoring of pore structures of phenolic resin derived carbon membranes

Jalil

Wang²,

Yacou

et al. 2017

Journal of Membrane Science

View full text Add to dashboard Cite

This work shows the preparation and separation performance assessment of carbon membranes derived from phenolic resin by a vacuum-assisted method and carbonisation in an inert atmosphere.The vacuum time played an important role in tailoring the structure of the membranes. For instance, pore volumes and surface areas increased from 0.81 and 834 to 2.2 cm 3 g -1 and 1910 m 2 g -1 , respectively, as the vacuum time exposure increased from 0 to 1200 s. The significant structural changes correlated very well with water permeation, as fluxes increased by 91% as the vacuum time increased from 0 to 1200s, reaching up to 169 kg m -2 h -1 at 5 bar. Molecular weight cut-off tests showed no rejection for the smaller glucose and sucrose molecules, though this increased to ~ 80% and full rejection for 36kD and 400kD polyvinyl pyrrolidine. Interestingly, FTIR spectra showed that the peaks of C-H stretching vibration (2800-3200 cm -1 ) and C-O stretching (1030 cm -1 ) became more pronounced as a function of increasing vacuum time, strongly suggesting that the use of vacuum further assisted in the polycondensation of phenolic oligomers. Based on these outcomes, a cluster to cluster model is proposed, whereby vacuum application promoted crosslinking reactions of the phenolic resin, creating microporous regions within the clusters, and mesoporous regions between the clusters. 2 Graphical AbstractKeywords: carbon membranes; vacuum-assisted method; water; molecular weight cut-off.

show abstract

“…Several studies have already indicated that the mesh-like structure formed from threads or fibers represents the most efficient structure for pressure-driven membrane-filtration processes [15][16][17][18][19][20]. Such a structure is able to achieve high selectivity while retaining extremely high filtration rates.…”

Section: Introductionmentioning

confidence: 99%

Integrating efficient filtration and visible-light photocatalysis by loading Ag-doped zeolite Y particles on filtration membrane of alumina nanofibers

Ribbens

Fan

et al. 2011

Journal of Membrane Science

View full text Add to dashboard Cite

a b s t r a c tFiltration membrane technology has already been employed to remove various organic effluents produced from the textile, paper, plastic, leather, food and mineral processing industries. To improve membrane efficiency and alleviate membrane fouling, an integrated approach is adopted that combines membrane filtration and photocatalysis technology. In this study, filtration membranes of alumina nanofibers (AF) with pore size of about 10 nm (determined by the liquid-liquid displacement method) have been synthesized through an in situ hydrothermal reaction, which permitted a large flux and achieved high selectivity. Silver nanoparticles (Ag NPs) are subsequently doped on the nanofibers of the membranes. Silver nanoparticles can strongly absorb visible light due to the surface plasmon resonance (SPR) effect, and thus induce photocatalytic degradation of organic dyes, including anionic, cationic and neutral dyes, under visible light irradiation. In this integrated system, the dyes are retained on the membrane surface, their concentration in the vicinity of the Ag NPs are high and thus can be efficiently decomposed under light irradiation. Meanwhile, the usual flux deterioration caused by the accumulation of the filtered dyes in the passage pores can be avoided. For example, when an aqueous solution containing methylene blue is processed using an integrated filtration membrane, a large flux of 200 L m −2 h −1 and a stable permeating selectivity of 85% were achieved. The combined visible light photocatalysis and filtration function leads to superior performance of the integrated membranes, which have a potential to be used for the removal of organic pollutants in drinking water.

show abstract

Ceramic membranes for separation of proteins and DNA through in situ growth of alumina nanofibres inside porous substrates

Cited by 25 publications

References 20 publications

Modeling colloid deposition on a protein layer adsorbed to iron-oxide-coated sand

Modeling colloid deposition on a protein layer adsorbed to iron-oxide-coated sand

Vacuum-assisted tailoring of pore structures of phenolic resin derived carbon membranes

Integrating efficient filtration and visible-light photocatalysis by loading Ag-doped zeolite Y particles on filtration membrane of alumina nanofibers

Contact Info

Product

Resources

About