2008
DOI: 10.1590/s0004-282x2008000600020
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Cerebellar glioblastoma mutiforme in an adult

Abstract: Eventhough supratentorial glioblastoma multiforme (GBM) is the most frequent primary brain tumor in adults, its localization in the cerebellum is extremely rare 1 . It is very important for the neurosurgeon to make the differential diagnosis between the cerebellar GBM, and other diseases like metastasis, anaplasic astrocytomas, and cerebellar infarct because their treatment modalities, prognosis, and outcome are different 2 . Clinical manifestations of these diseases are very similar, so making an appropriate … Show more

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Cited by 6 publications
(12 citation statements)
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“…However, infratentorial GBM is rare, and it accounts for 0.5%-l% of all intracranial GBM [1,2], only a few individual cases are reported [1,[3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. The largest-scale reports to date are a multicenter clinical retrospective study (including 45 patients) and a single-center (including 21 patients) clinical retrospective study [3,12].…”
Section: Introductionmentioning
confidence: 99%
“…However, infratentorial GBM is rare, and it accounts for 0.5%-l% of all intracranial GBM [1,2], only a few individual cases are reported [1,[3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. The largest-scale reports to date are a multicenter clinical retrospective study (including 45 patients) and a single-center (including 21 patients) clinical retrospective study [3,12].…”
Section: Introductionmentioning
confidence: 99%
“…More mitotic figures with high leveling index will differentiate it from anaplastic astrocytoma. [4]…”
Section: Discussionmentioning
confidence: 99%
“…Giant cell GBM predominates in cerebral hemispheres mainly temporal and parietal lobes but cerebellum, lateral ventricles, and spinal cord are rare sites. [4] The mean age at clinical presentation is fourth decades of life and affects males more frequently than females (M:F ratio is 1:6). [34]…”
Section: Discussionmentioning
confidence: 99%
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“…In Brazil, literature about GBMO is scarce, although some cases of GBMs have been reported, most of it was in adults and located in the cerebellum [7]. Furthermore, cases related regarding specifically pediatric patients include a cerebral case, located in the right hemisphere [8].…”
Section: Introductionmentioning
confidence: 99%