Cerebral abscess and calvarial osteomyelitis caused by Burkholderia pseudomallei in a renal transplant recipient

Abstract

Melioidosis is an infection of humans caused by the saprophytic bacterium Burkholderia (previously Pseudomonas) pseudomallei. We present a patient of cerebral abscess and calvarial osteomyelitis caused by B. pseudomallei in a renal transplant recipient. We treated the patient with ceftazidime for 3 weeks, followed by trimethoprim‐sulfamethoxazole (TMP‐SMX) for 6 months. The superficial abscess reduced in size at the end of first month and subsided gradually. A repeat MRI showed reduction in intracranial abscess. The patient had no neurological deficit.

Multi-systemic melioidosis in a patient with type 2 diabetes in non-endemic areas: A case report and review of literature

“…Physicians who are unfamiliar with the treatment of melioidosis should follow the course of treatment recommended by the guidelines[ 45 , 46 ]. Although antibiotics are preferred for the treatment of multiple intracranial abscesses in melioidosis[ 47 ]. Adjunctive abscess drainage was performed in 58% cases.…”