Cerebral aneurysms in childhood

Wojtacha, Maciej; Bazowski, P; Mandera, Marek; Krawczyk, Ireneusz; Rudnik, Adam

doi:10.1007/s003810000378

Cited by 39 publications

(20 citation statements)

References 20 publications

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“…19) The male dominance among patients with SAH has been observed in childhood and adolescence, whereas the female preponderance with male to female ratio of 2:1 is frequently observed in adult group of patients. 6,9,20) The reports on the sex dominance in young adults are variable. 5,7,11,14,21) A slight male dominance was noted (58.3%) in the present study.…”

Section: Discussionmentioning

confidence: 99%

“…The clinical parameters, risk factors, location, size, multiplicity, and intraoperative as well as perioperative factors have been studied in young adults with aneurysmal SAH. 6,15,20) Even so, elucidation of factors that might predict the outcomes in young adults is lacking in the current neurosurgical literature. The present study analyzed the predictors of outcome at discharge and the independent predictors of the long-term outcome in this subgroup of the population.…”

Section: Introductionmentioning

confidence: 99%

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Prediction of Outcomes in Young Adults With Aneurysmal Subarachnoid Hemorrhage

Chotai

Moon

et al. 2013

Neurol. Med. Chir.(Tokyo)

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Subarachnoid hemorrhage (SAH) is rare in young adults and little is known about aneurysms in this subgroup. The effect of clinical and prognostic factors on the outcome based on the Glasgow Outcome Scale (GOS) scores and the predictors of unfavorable outcomes were analyzed in young adults with aneurysmal SAH. A retrospective review of the clinical parameters, including age, sex, hypertension, smoking status, hyperlipidemia, location of the cerebral aneurysm, size of the aneurysm, multiplicity, perioperative complication such as hydrocephalus, vasospasm, and hematoma, and Hunt and Hess and Fisher grading on presentation, was conducted in 108 young adults (mean age 34.8 years) managed at our institute. The outcome was classified based on GOS grading into unfavorable (GOS scores 1-3) or favorable (GOS scores 4 or 5). The overall mortality rate was 3.7% (4/108 patients). Univariate regression analysis for the outcomes at discharge found that age at the time of presentation, male sex, size of aneurysm, multiple aneurysms, hyperlipidemia, and poor Hunt and Hess and Fischer grades were associated with unfavorable outcome. Multivariate regression analysis found independent effects of sex, multiple aneurysms, size of aneurysm, and Hunt and Hess grade on the outcome at discharge. Size of aneurysm, presence of multiple aneurysms, Hunt and Hess grade, and hypertension were the predictors of outcome at mean 2-year follow up based on multivariate exact regression analysis. The multimodal approach with aggressive medical management, early intervention, and surgical treatment might contribute to favorable long-term outcomes in patients with poor expected outcomes.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Prediction of Outcomes in Young Adults With Aneurysmal Subarachnoid Hemorrhage

Chotai

Moon

et al. 2013

Neurol. Med. Chir.(Tokyo)

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“…Although the clinical characteristics of aneurysmal SAH have been widely studied in the general population, there is controversy regarding aneurysm formation and rupture in young adults. [2][3][4] Generally, females are at higher risk in aneurysmal SAH. 5 Furthermore, it is thought that females have a poorer prognosis.…”

Section: Introductionmentioning

confidence: 99%

Aneurysmal subarachnoid hemorrhage in young adults: A gender comparison study

Park¹,

Kim²,

Kim³

et al. 2008

Journal of Clinical Neuroscience

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“…Пî äàííым F. Proust è ñîàâòîðîâ [33], ó 36,4% äåòåé äàaeå ïðè íàëèчèè àíãèîãðàфèчåñêè ïîäòâåðaeäåííîãî àíãèîñïàзмà íåâðîëîãèчåñêèå ñèмïòîмы îòñóòñòâîâàëè. Â òî aeå âðåмя, ðèñê âîзíèêíîâåíèя ïîâòîðíîãî êðîâîèзëèя-íèя ó äåòåé зíàчèòåëüíî âышå, чåм ó âзðîñëых, è ñîñòàâëяåò îêîëî 60% [40].…”

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Arterial aneurysms of the brain at children

Orlov¹

2008

Ukr Neurosurg J

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Àðòåðèàëьíыå àíåâðèçìы ãîëîâíîãî ìîçãà ó äåòåéÎðëîâ Ì.Þ. ÃУ «Иíñòèòóò íåéðîхèðóðãèè èì. àêàä. À.Ï. Ðîìîäàíîâà ÀÌÍ Уêðàèíы», ã. КèåâПðåäñòàâëåíы ñîâðåмåííыå ñâåäåíèя îб эïèäåмèîëîãèè, êëèíèчåñêèх ïðîяâëåíèях, äèà-ãíîñòèêå è ðàзëèчíых мåòîäàх ëåчåíèя àðòåðèàëüíых àíåâðèзм (АА) ãîëîâíîãî мîзãà ó äåòåé. Óëóчшåíèå äèàãíîñòèчåñêèх âîзмîaeíîñòåé â íåéðîхèðóðãèè èзмåíèëî ïðåäñòàâëåíèå î ðåäêîñòè äàííîé ïàòîëîãèè ó äåòåé, â ñâязè ñ чåм âîзíèêëî мíîãî ïðîбëåм, òðåбóющèх ðåшåíèя.Кëючåâыå ñëîâà: артериальные аневризмы, эпидемиология, клинические проявления, диагностика, лечение, дети.Частота и локализация артериальных анев-ризм головного мозга у детей. Â эòèîïàòîãåíåòèчåñ-êèх êëàññèфèêàöèях АА ãîëîâíîãî мîзãà âыäåëåíà ãðóïïà äèзэмбðèîãåíåòèчåñêèх (âðîaeäåííых, мëà-äåíчåñêèх, äåòñêèх) àíåâðèзм [1-3, 19, 21, 22, 29]. Чàñòîòà èх, ïî äàííым îбñëåäîâàíèя бîëüшèх ãðóïï ïàöèåíòîâ, ñîñòàâëяåò îò 0,17 äî 5% âñåх äèàãíîñòè-ðîâàííых АА â ïîïóëяöèè (ñì. òàбëèöó).

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Cerebral aneurysms in childhood

Abstract: We suggest that the very good outcome (100% very good results in patients operated on early) obtained and the high risk of rebleeding in children with cerebral aneurysm allow the recommendation of early surgery in children with ruptured cerebral aneurysms.

Cited by 39 publications

References 20 publications

Prediction of Outcomes in Young Adults With Aneurysmal Subarachnoid Hemorrhage

Prediction of Outcomes in Young Adults With Aneurysmal Subarachnoid Hemorrhage

Aneurysmal subarachnoid hemorrhage in young adults: A gender comparison study

Arterial aneurysms of the brain at children

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