Cerebral blood flow: measurement with xenon-enhanced dynamic helical CT.

Abstract

This volumetric CBF mapping method is applicable in clinical practice because of the short examination time and acceptable radiation dose.

Understanding and treating moyamoya disease in children

“…Such techniques, which include Xe-enhanced CT, PET, and SPECT, can identify regional perfusion instability prior to treatment and ascertain the extent of improvement of functional perfusion following therapy. 60,62,74,108 Single photon emission CT, with and without acetazolamide/CO 2 vasodilatory challenge, is a particularly useful technique that assesses cerebrovascular reserve and helps to predict the likelihood of further disease progression. Occlusion of the major cerebral arteries in patients with moyamoya produces chronic hemodynamic stress.…”

Quantitative Cerebral Perfusion Imaging in Children and Young Adults with Moyamoya Disease: Comparison of Arterial Spin-Labeling-MRI and H2[15O]-PET

“…To determine the optimal targets for revascularization procedures as well as for postoperative follow-up, CBF studies with the use of Xe-CT, SPECT, or PET have been shown to be of high clinical value. [3][4][5][6][7] However, these methods are associated with ionizing radiation, which should be minimized or avoided whenever possible and especially in young patients. Recently, interest in MR imaging techniques for CBF assessment has grown, and initial evaluation of these techniques has been undertaken in patients with Moyamoya disease.…”

10 Pediatric Moyamoya Disease

“…Cerebral blood flow techniques are very useful in diagnosis and management of MMD, which include Xe-enhanced CT, PET and SPECT that assess cerebrovascular reserve as well as disease progression [32][33][34].…”