Cerebral blood perfusion and neurobehavioral performance in full-term small-for-gestational-age fetuses

Cruz‐Martínez, R.; Figueras, F.; Orós, Daniel; Padilla, Nelly; Meler, E.; Hernández‐Andrade, Edgar; Gratacós, Eduard

doi:10.1016/j.ajog.2009.05.028

Cited by 110 publications

(96 citation statements)

References 39 publications

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“…In mild cases of fetal hypoxia when the resistance of the umbilical artery is increased, no change maybe demonstrated in the flow pattern of the MCA due to the adaptation of the fetal circulation in maintaining the after load of the left ventricle 16 . An increase in the MCA PSV maybe the only perceivable finding at this early stage 17 .…”

Section: Fetal Cerebral Circulationmentioning

confidence: 97%

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Colour Doppler in IUGR- Where are we and where do we go?

Lulla

Garg

2010

J Obstet Gynecol India

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Intra-uterine growth restriction (IUGR) is an important perinatal problem giving rise to increased morbidity and mortality in the growth restricted fetus. The aim of fetal medicine today, is to prevent the mere occurrence of IUGR in high risk pregnancies and to deliver the fetuses already afflicted with growth restriction, before they have suffered from the effects of hypoxia. The use of Doppler provides this information, which is not readily obtained from the other conventional tests of fetal well being. The Doppler patterns follow a longitudinal trend in the arterial and venous circulation of the fetus as well as the placental vasculature guiding management decisions regarding the appropriate time of delivery. Progressive knowledge of the fetal circulation and its adaptation when the fetus is subjected to hypoxia, has helped us recognize the early signs of IUGR thereby improving the prognosis of these complicated pregnancies. It has therefore become the gold standard in the management of the growth-restricted fetus.

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Section: Fetal Cerebral Circulationmentioning

confidence: 97%

“…Presumably, this reflects a terminal decompensation in the setting of acidemia or brain edema. When brain edema becomes severe, reversal of diastolic flow maybe seen due to the raised intracranial tension, which suggests grave and irreversible fetal neurological outcome 16 .…”

Section: Fetal Cerebral Circulationmentioning

confidence: 99%

Colour Doppler in IUGR- Where are we and where do we go?

Lulla

Garg

2010

J Obstet Gynecol India

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“…Progressive hypoxia leads to academia and there is (Table 1 and Figure 3). [17,22,23] Resistance Index (RI)…”

Section: Pimentioning

confidence: 99%

Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study

Desai¹,

Tiwale²,

Devar³

et al. 2017

Natl J Physiol Pharm Pharmacol

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Background: Doppler velocimetry studies of placental and fetal circulation can provide important information regarding fetal well-being providing an opportunity to improve fetal outcome. Aims and Objective: The aim of this study to evaluate the role of color Doppler velocimetry of the fetal middle cerebral artery (MCA) velocity waveforms, systolic/diastolic ratio (S/D), pulsatility index (PI), and resistance index (RI) in intrauterine growth restriction (IUGR) pregnancies in II and III trimesters. Materials and Methods: This was a cross-sectional study. The control and study groups were studied in II and III trimesters. They were first subjected to ultrasonography biometry and then to MCA Doppler sonography. The statistical analysis was performed by "unpaired" and "paired" t-test. Results: In both control and study groups, the values of S/D ratio, PI, and RI in MCA decline during II to III trimester. The values were lower in the study group as compared to the control group. Thus that the present study predicts were; (a) lower PI values were suggestive of fetal hypoxia, (b) The lower values are due to vasodilatation due to hypoxia to supply more blood to the brain to protect it from the damaging effects of hypoxia. Thus, the brain is spared from damage. Conclusion: Doppler can be considered as one of the important non-invasive techniques to assess the fetomaternal and uteroplacental circulations. The MCA indices were valuable for predicting the outcome of IUGR pregnancies.

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“…이러한 차이는 대뇌혈관의 확장이 방어 기전으로 여겨 지거나, 반대로 신경학적 발달이상의 원인으로 보고되기 때문이다. 신경 발달 결과에 대한 초기 연구에서는 뇌보존이 심한 뇌손상을 막기 위한 적응이라고 보고되었지만 [54], 최근 만삭의 부당경량아 태아에서 중대 뇌동맥 재분배만 있는 경우 신생아에서 비정상적인 신경행동의 위험이 있고 [55], 2세가 되었을 때 약간의 신경발달 지연이 있어 재분배가 오히 려 불량한 예후의 예측인자가 될 수 있다 [56]. 중대뇌동맥의 도플러 소 견과 신경학적 예후와의 관련에 대한 추가적인 연구가 필요하다.…”

Section: ) 중대뇌동맥unclassified

New aspect in management of fetal growth restriction

Kim

2011

Korean J Obstet Gynecol

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Fetal growth restriction (FGR) is one of the most common and complex diseases and it is associated with increased perinatal mortality and morbidity. FGR influences the long-term health of neonates and their offspring. The aim of obstetric management is to identify growth-restricted fetuses at risk of severe intrauterine hypoxia, to monitor their health and to deliver when the adverse outcome is imminent. This review aims to investigate the new aspects of FGR including the diagnosis, antenatal surveillance, and clinical management. Keywords 임신 주수와 태아 성장의 정확한 측정

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Cerebral blood perfusion and neurobehavioral performance in full-term small-for-gestational-age fetuses

Cited by 110 publications

References 39 publications

Colour Doppler in IUGR- Where are we and where do we go?

Colour Doppler in IUGR- Where are we and where do we go?

Evaluation of fetal middle cerebral artery Doppler indices in pregnancies with intrauterine growth restriction: A cross-sectional study

New aspect in management of fetal growth restriction

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