Cerebral High Grade Glioma with Crossed Cerebellar Metastases: A Report of Three Cases

Abstract

We describe three patients with high grade supratentorial gliomas who were operated and later presented with cerebellar mass lesions on the opposite side. Supratentorial infarct with crossed cerebellar atrophy is a well-known entity called crossed cerebellar diaschisis. We hypothesize that supratentorial high grade tumours might also spread to the opposite cerebellum through crossed cerebrocerebellar fiber tracts similar to crossed cerebellar diaschisis.

Midazolam Sedation Induces Upper Limb Coordination Deficits That Are Reversed by Flumazenil in Patients with Eloquent Area Gliomas

“…Such maladaptive processes have been reported in patients with intracranial tumors. [22][23][24] Instead of being confined to a single area, the pathologic perturbations from the tumor influence brain across many regions, illustrating complex neural architecture and interconnections. In our study, the phenomenon of diaschisis was hidden in our patients because of adaptive compensation processes, but it was unmasked by midazolam sedation and then hidden again after sedation reversal.…”