Cerebral intraparenchymal extramedullary hematopoiesis in polycythemia vera

Boban, Jasmina; Kalhs, Peter; Thurnher, Majda M.

doi:10.1007/s13760-019-01196-2

Acta Neurol Belg

2019

DOI: 10.1007/s13760-019-01196-2

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Cerebral intraparenchymal extramedullary hematopoiesis in polycythemia vera

Jasmina Boban

Peter Kalhs

Majda M. Thurnher

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2023

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Report of a Rare Case of Intracranial Extramedullary Hematopoiesis Mimicking a Brain Tumor

Habib¹,

Abu-Abaa²,

Chen³

2023

Cureus

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Failure of the bone marrow to maintain adequate blood cell production to match blood metabolic demand incites the production of cell lines outside the bone marrow, which is known as extramedullary hematopoiesis. Herein, we are reporting an 80-year-old male patient who presented with two weeks of worsening headaches and behavioral changes. Labs showed thrombocytosis and imaging showed a large right-sided hemorrhagic brain mass. No evidence of malignancy was seen elsewhere. Brain mass biopsy showed intracranial extramedullary hematopoiesis (IEMH) and bone marrow biopsy confirmed the diagnosis of essential thrombocythemia (ET)/myelofibrosis. This case adds to a few reported cases of IEMH, and to the best of our knowledge, this is the first reported case of IEMH in association with ET. It helps remind clinicians to keep IEMH in the differential diagnosis of those presenting with signs and symptoms of elevated intracranial pressure (ICP) and a newly found brain mass on the background of previously diagnosed or suspected myeloproliferative neoplasms.

show abstract

Report of a Rare Case of Intracranial Extramedullary Hematopoiesis Mimicking a Brain Tumor

Habib¹,

Abu-Abaa²,

Chen³

2023

Cureus

View full text Add to dashboard Cite

show abstract

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Cerebral intraparenchymal extramedullary hematopoiesis in polycythemia vera

Cited by 1 publication

References 6 publications

Report of a Rare Case of Intracranial Extramedullary Hematopoiesis Mimicking a Brain Tumor

Report of a Rare Case of Intracranial Extramedullary Hematopoiesis Mimicking a Brain Tumor

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