Cerebral lateralization in individuals diagnosed as autistic in early childhood

Measuring the Plasticity of Social Approach: A Randomized Controlled Trial of the Effects of the PEERS Intervention on EEG Asymmetry in Adolescents with Autism Spectrum Disorders

“…In ASD, studies have shown a negative effect on skills/tasks lateralized to the left hemisphere (Dawson et al 1982(Dawson et al , 1986Dawson 1983;Dawson and Fernald 1987;Gunter et al 2002;Rinehart et al 2002;Sabbagh 1999;Shamay-Tsoory et al 2010); and an unexpected right hemisphere advantage on certain tasks (Ashwin et al 2005). Neurologically, research has demonstrated decreases in activity (Dawson et al 1995;Stroganova et al 2007) and blood flow (Chiron et al 1995) in the left hemisphere; significantly increased activity in the right frontal and temporal lobes, versus controls (Kleinhans et al 2008); a lack of expected leftward structural asymmetry in gray and white matter, versus controls (Haznedar et al 2006;Lo et al 2011;Wan et al 2012); and an abnormal enlargement of the right hemisphere (Herbert et al 2005), all perhaps suggesting hyper-activation of the right hemisphere and hypo-activation of the left hemisphere in ASD (Shamay-Tsoory et al 2010).…”

Short‐latency somatosensory evoked potentials in infantile autism: evidence of hyperactivity in the right primary somatosensory area

“…[5][6][7] Nevertheless, few studies have comprehensively examined somatosensory function in infantile autism using short-latency somatosensory evoked potentials (S-SEPs). 8 In contrast, results of dichotic listening tests, which can identify the dominant hemisphere with respect to auditory function, as well as electroencephalogram (EEG) examinations, 9,10 suggest that right cerebral hemispheric predominance in children with autism contributes significantly to this disorder. In addition, neuropsychological tests have indicated that certain children with autism and very low verbal function have normal or nearly normal visuospatial function.…”

L’autisme : vers une nécessaire révolution culturelle

“…Un retard dans la maturation céré-brale a été détecté, notamment au niveau du cervelet ou du système limbique [18], mais ces anomalies céré-brales ne sont pas systématiquement observées. Des études sur la latéralisation indiquent un hémisphère droit hyperactivé au détriment de l'hémisphère gauche (spécialisé dans le langage et les fonctions symboliques), même si tous les autistes ne présentent pas un schéma de latéralisation anormal [19]. Les études en imagerie fonctionnelle cérébrale révèlent une hypoactivité dans certaines régions du cerveau (lobe frontal, préfrontal ou gyrus cingulaire).…”